RXN-14959

Reaction RXN-14959

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-2.8.1.8
• common name:
  • lipoyl synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 S-ADENOSYLMETHIONINE[c] + 1 a-2-oxoglutarate-dehydrogenase-E2-protei[c] + 2 Reduced-2Fe-2S-Ferredoxins[c] + 2 Sulfurated-Sulfur-Acceptors[c] => 2 MET[c] + 2 Unsulfurated-Sulfur-Acceptors[c] + 1 Oxo-glutarate-dehydrogenase-lipoyl[c] + 2 CH33ADO[c] + 2 Oxidized-2Fe-2S-Ferredoxins[c]
• With common name(s):
  • 2 S-adenosyl-L-methionine[c] + 1 a [2-oxoglutarate-dehydrogenase E2 protein] N6-octanoyl-L-lysine[c] + 2 a reduced [2Fe-2S] ferredoxin[c] + 2 a sulfurated [sulfur carrier][c] => 2 L-methionine[c] + 2 an unsulfurated [sulfur carrier][c] + 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] + 2 5'-deoxyadenosine[c] + 2 an oxidized [2Fe-2S] ferredoxin[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ04393
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ11692
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ03663
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER

Pathways

• PWY-7382, lipoate biosynthesis and incorporation (yeast): PWY-7382
  • 4 reactions found over 7 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools