METHYLENETHFDEHYDROG-NADP-RXN

Reaction METHYLENETHFDEHYDROG-NADP-RXN

• direction:
  • REVERSIBLE
• ec number:
  • EC-1.5.1.5
• common name:
  • methylenetetrahydrofolate dehydrogenase (NADP+)
  • methylenetetrahydrofolate dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 METHYLENE-THF-GLU-N[c] + 1 NADP[c] <=> 1 5-10-METHENYL-THF-GLU-N[c] + 1 NADPH[c]
• With common name(s):
  • 1 a 5,10-methylene-tetrahydrofolate[c] + 1 NADP+[c] <=> 1 a 5,10-methenyltetrahydrofolate[c] + 1 NADPH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ11954
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ02262
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ12991
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ02922
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ10799
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ17385
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-5497, purine nucleobases degradation II (anaerobic): PWY-5497
  • 10 reactions found over 24 reactions in the full pathway
• PWY-3841, folate transformations II: PWY-3841
  • 9 reactions found over 11 reactions in the full pathway
• PWY-2201, folate transformations I: PWY-2201
  • 9 reactions found over 12 reactions in the full pathway
• PWY-7909, formaldehyde oxidation VII (THF pathway): PWY-7909
  • 3 reactions found over 4 reactions in the full pathway
• 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
  • 8 reactions found over 9 reactions in the full pathway
• CODH-PWY, reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): CODH-PWY
  • 4 reactions found over 9 reactions in the full pathway
• PWY-1722, formate assimilation into 5,10-methylenetetrahydrofolate: PWY-1722
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 22815
• LIGAND-RXN:
  • R01220
• UNIPROT:
  • P09440
  • P07245
  • P11586
  • P44313
  • P47259
  • P54382
  • O67736
  • Q9JWI9
  • Q9PP68
  • P24186
  • Q60006
  • Q27772
  • P51696
  • O65269
  • O65271
  • O68031
  • Q9ZTV0
  • Q9X7F6