RXN0-1133

Reaction RXN0-1133

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-2.3.1.12
• common name:
  • lipoate acetyltransferase
  • pyruvate dehydrogenase (NAD+)
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CO-A[c] + 1 Pyruvate-dehydrogenase-acetylDHlipoyl[c] => 1 ACETYL-COA[c] + 1 Pyruvate-dehydrogenase-dihydrolipoate[c]
• With common name(s):
  • 1 coenzyme A[c] + 1 a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine[c] => 1 acetyl-CoA[c] + 1 a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ00971
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ17268
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ10087
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ13527
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ10725
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ01042
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ10792
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER

Pathways

• PYRUVDEHYD-PWY, pyruvate decarboxylation to acetyl CoA: PYRUVDEHYD-PWY
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R02569
• UNIPROT:
  • Q01991
  • P12695
  • Q7M2M8
  • P10515
  • Q39082
  • Q9TRP7
  • Q7M0X6
  • Q59098
  • Q9PF09
  • P35489
  • P21883
  • Q59658
  • Q9JU07
  • Q59298
  • P45118
  • Q54102
  • P11961
  • Q59821
  • P08461
  • Q16791
  • Q41737
  • O64968
  • P10802
  • P06959