SQUALENE-MONOOXYGENASE-RXN

Reaction SQUALENE-MONOOXYGENASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing)
• ec number:
  • EC-1.14.14.17
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 OXYGEN-MOLECULE[c] + 1 SQUALENE[c] + 1 Red-NADPH-Hemoprotein-Reductases[c] => 1 WATER[c] + 1 EPOXYSQUALENE[c] + 1 Ox-NADPH-Hemoprotein-Reductases[c]
• With common name(s):
  • 1 oxygen[c] + 1 squalene[c] + 1 a reduced [NADPH-hemoprotein reductase][c] => 1 H2O[c] + 1 (3S)-2,3-epoxy-2,3-dihydrosqualene[c] + 1 an oxidized [NADPH-hemoprotein reductase][c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ00579
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-5670, epoxysqualene biosynthesis: PWY-5670
  • 2 reactions found over 2 reactions in the full pathway
• PWY-6098, diploterol and cycloartenol biosynthesis: PWY-6098
  • 2 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R02873
  • R02874
• UNIPROT:
  • P52020
  • P32476
  • Q9T064
  • O65829
  • O65726
  • O65727
  • O65402
  • O65403
  • O65404