1.14.21.6-RXN

Reaction 1.14.21.6-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 5α-cholest-7-en-3β-ol,NAD(P)H:oxygen 5-oxidoreductase
• ec number:
  • EC-1.14.19.20
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 PROTON[c] + 1 OXYGEN-MOLECULE[c] + 1 CPD-4186[c] + 2 FERROCYTOCHROME-B5[c] => 1 CPD-4187[c] + 2 WATER[c] + 2 FERRICYTOCHROME-B5[c]
• With common name(s):
  • 2 H+[c] + 1 oxygen[c] + 1 lathosterol[c] + 2 a ferrocytochrome b5[c] => 1 7-dehydrocholesterol[c] + 2 H2O[c] + 2 a ferricytochrome b5[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ00834
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ11625
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY66-341, cholesterol biosynthesis I: PWY66-341
  • 14 reactions found over 22 reactions in the full pathway
• PWY66-3, cholesterol biosynthesis II (via 24,25-dihydrolanosterol): PWY66-3
  • 12 reactions found over 22 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 18924
  • 18920
• LIGAND-RXN:
  • R07215