RXN-12848

Reaction RXN-12848

• direction:
  • LEFT-TO-RIGHT
• common name:
  • cholest-4-en-3-one 26-monooxygenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 OXYGEN-MOLECULE[c] + 1 NADH[c] + 1 PROTON[c] + 1 CPD-323[c] => 1 WATER[c] + 1 NAD[c] + 1 CPD-13887[c]
• With common name(s):
  • 1 oxygen[c] + 1 NADH[c] + 1 H+[c] + 1 cholest-4-en-3-one[c] => 1 H2O[c] + 1 NAD+[c] + 1 (25S)-26-hydroxycholest-4-en-3-one[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ20106
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM

Pathways

• PWY-6946, cholesterol degradation to androstenedione II (cholesterol dehydrogenase): PWY-6946
  • 6 reactions found over 22 reactions in the full pathway
• PWY-6945, cholesterol degradation to androstenedione I (cholesterol oxidase): PWY-6945
  • 5 reactions found over 17 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 31946
• LIGAND-RXN:
  • R09859