2.4.1.119-RXN

Reaction 2.4.1.119-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • dolichyl-diphosphooligosaccharide-protein glycotransferase
  • dolichyl-diphospho-oligosaccharide-protein glycosyltransferase
• ec number:
  • EC-2.4.99.18
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 Protein-L-Asparagine[c] + 1 CPD-18076[c] => 1 CPD-224[c] + 1 CPD-18077[c] + 1 PROTON[c]
• With common name(s):
  • 1 a [protein]-L-asparagine[c] + 1 α-D-Glc-(1→2)-α-D-Glc-(1→3)-α-D-Glc-(1→3)-α-D-Man-(1→2)-α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→2)-α-D-Man-(1→6)]-α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol[c] => 1 a dolichyl diphosphate[c] + 1 a [protein]-L-asparagine-[(glucosyl)3(mannosyl)9(N-acetylglucosaminyl)2][c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ18586
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ12004
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ19404
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ02055
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ08534
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ04308
  • Source: orthology-ectocarpus_siliculosus

Pathways

• MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS, protein N-glycosylation (eukaryotic, high mannose): MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
  • 19 reactions found over 19 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• UNIPROT:
  • P39656
  • P48440
  • P41543
  • P80896
  • P80897
  • P48439
  • P46964
  • Q92316
  • Q10176