RXN-12693

Reaction RXN-12693

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-beta-hydroxy-delta5-steroid dehydrogenase
• ec number:
  • EC-1.1.1.145
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CHOLESTEROL[c] + 1 NAD[c] => 1 NADH[c] + 1 CPD-13684[c] + 1 PROTON[c]
• With common name(s):
  • 1 cholesterol[c] + 1 NAD+[c] => 1 NADH[c] + 1 cholest-5-en-3-one[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ19982
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ10400
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21137
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03341
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21018
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02713
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19806
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ17700
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ10476
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ05616
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21972
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ04385
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ04782
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ21834
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ01092
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16241
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ06332
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ08509
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03340
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM

Pathways

• PWY-6946, cholesterol degradation to androstenedione II (cholesterol dehydrogenase): PWY-6946
  • 6 reactions found over 22 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools