RXN-12705

Reaction RXN-12705

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-hydroxyacyl-CoA dehydrogenase
• ec number:
  • EC-1.1.1.35
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-13694[c] + 1 NAD[c] => 1 PROTON[c] + 1 CPD-13695[c] + 1 NADH[c]
• With common name(s):
  • 1 24-hydroxy-3-oxocholest-4-en-26-oyl-CoA[c] + 1 NAD+[c] => 1 H+[c] + 1 3,24-dioxocholest-4-en-26-oyl-CoA[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ07211
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ01444
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ16180
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ17348
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16470
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03584
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ06127
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21390
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM

Pathways

• PWY-6946, cholesterol degradation to androstenedione II (cholesterol dehydrogenase): PWY-6946
  • 6 reactions found over 22 reactions in the full pathway
• PWY-6945, cholesterol degradation to androstenedione I (cholesterol oxidase): PWY-6945
  • 5 reactions found over 17 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools