UBIQUITIN--PROTEIN-LIGASE-RXN

Reaction UBIQUITIN--PROTEIN-LIGASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • ubiquitin-protein transferase
  • ubiquitin:[E1 ubiquitin-activating enzyme] ligase
• ec number:
  • EC-6.2.1.45
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 Ubiquitin-C-Terminal-Glycine[c] + 1 ATP[c] + 1 Ubiquitin-activating-protein-E1-L-cys[c] => 1 AMP[c] + 1 S-ubiquitinyl-UAP-E1-L-cysteine[c] + 1 PPI[c]
• With common name(s):
  • 1 a [ubiquitin] C-terminal glycine[c] + 1 ATP[c] + 1 an [E1 ubiquitin-activating enzyme]-L-cysteine[c] => 1 AMP[c] + 1 an S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine[c] + 1 diphosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ18583
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02976
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02926
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ13312
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16898
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00224
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ04560
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02681
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ13742
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ06450
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ07569
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03332
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02053
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21688
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ20496
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16890
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00781
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ18681
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ07231
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ00403
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19416
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ14705
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ05166
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ20646
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ08236
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02273
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03227
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21005
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ20672
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ13409
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ14056
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ12161
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19693
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ06138
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00071
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ08227
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00294
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ09535
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19385
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ13813
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ07508
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02712
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ12965
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16295
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ10355
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ19160
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00804
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ01027
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ00318
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ11943
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ00056
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03333
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19910
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00945
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ06699
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16614
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ05813
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ07684
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ13418
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ17379
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ04757
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ09214
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ07902
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ06602
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ07230
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ15747
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ12138
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ12663
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ14442
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ10760
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ20124
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ05989
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ14102
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ01128
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ13626
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ22265
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ14443
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ17050
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ22472
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ05828
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ13415
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ17906
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ06595
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21686
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ17724
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ10665
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02299
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ10722
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ20603
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ01397
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ20785
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ04102
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16378
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16897
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ10358
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21419
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ17121
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19152
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03300
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ20681
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ12751
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ06452
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ06449
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ08163
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ01371
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ09227
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02711
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ05155
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ11923
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02709
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21877
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ04322
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ03727
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ09421
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00975
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ09006
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ22635
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ00935
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ15828
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00972
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16104
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ05626
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ10664
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19061
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00876
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02714
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ14399
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ00413
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00896
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16029
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ07373
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ09000
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ13840
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ06889
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ14051
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ17660
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ04994
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03726
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ06991
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ17713
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19253
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ22197
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ01365
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03110
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19309
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ06176
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ18713
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ07233
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ08129
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ15544
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ13673
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ06876
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ15189
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00337
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ22393
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ19700
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ11884
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM

Pathways

• PWY-7511, protein ubiquitylation: PWY-7511
  • 9 reactions found over 9 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R03876
• UNIPROT:
  • P22314
  • P49459
  • P62256
  • P63146
  • P28263
  • Q02053
  • P62257
  • P61088
  • P63279
  • P19812
  • P21734
  • P25869
  • P31254
  • P15731
  • P15732
  • P29340
  • P35133
  • P35134
  • P35132
  • P33296
  • P22515
  • P39940
  • P42748
  • P42750
  • P42749
  • P42747
  • P50623
  • Q42973
  • P40984
  • Q92462
  • Q42540
  • P93028
  • P93393
  • P31252
  • P52486
  • Q9YGM6
  • O42646
  • O15979
  • P23566
  • Q96PU5
  • P27949

"ubiquitin:[E1 ubiquitin-activating enzyme] ligase" cannot be used as a page name in this wiki.