RXN66-305

Reaction RXN66-305

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 14-oxolanosterol deformylase
  • 4,4-dimethyl-14α-formyl-5α-cholesta-8,24-dien-3β-ol,NADPH:oxygen oxidoreductase (14-methyl cleaving)
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-4573[c] + 1 NADPH[c] + 1 OXYGEN-MOLECULE[c] => 1 44-DIMETHYL-CHOLESTA-814-24-TRIENOL[c] + 1 NADP[c] + 1 WATER[c] + 1 FORMATE[c]
• With common name(s):
  • 1 14-oxolanosterol[c] + 1 NADPH[c] + 1 oxygen[c] => 1 4,4-dimethyl-cholesta-8,14,24-trienol[c] + 1 NADP+[c] + 1 H2O[c] + 1 formate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ05072
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY66-341, cholesterol biosynthesis I: PWY66-341
  • 14 reactions found over 22 reactions in the full pathway
• PWY66-4, cholesterol biosynthesis III (via desmosterol): PWY66-4
  • 14 reactions found over 22 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools