Difference between revisions of "FOLYLPOLYGLUTAMATESYNTH-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-11444 CPD-11444] == * smiles: ** C(=O)([O-])CCC5(=C4(NC(CC1(NC(=C(CC([O-])=O)C(CCC(=O)[O-])...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=FOLYLPOLYGLUTAMATESYNTH-RXN FOLYLPOLYGLUTAMATESYNTH-RXN] == * direction: ** LEFT-TO-RIGHT * common...")
 
(2 intermediate revisions by the same user not shown)
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-11444 CPD-11444] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=FOLYLPOLYGLUTAMATESYNTH-RXN FOLYLPOLYGLUTAMATESYNTH-RXN] ==
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* smiles:
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* direction:
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** C(=O)([O-])CCC5(=C4(NC(CC1(NC(=C(CC([O-])=O)C(CCC(=O)[O-])=1)CC2(NC(=C(C(CCC(=O)[O-])=2)CC(=O)[O-])CC3(=C(CCC([O-])=O)C(CC(=O)[O-])=C(N3)C4))))=C(CC(=O)[O-])5))
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** LEFT-TO-RIGHT
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* inchi key:
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** InChIKey=QTTNOSKSLATGQB-UHFFFAOYSA-F
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* common name:
 
* common name:
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** uroporphyrinogen-I
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** folylpolyglutamate_synthase
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* molecular weight:
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** bifunctional_protein
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** 828.742   
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* ec number:
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** [http://enzyme.expasy.org/EC/6.3.2.17 EC-6.3.2.17]
 
* Synonym(s):
 
* Synonym(s):
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** uroporphyrinogen I
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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== Reaction(s) known to produce the compound ==
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* With identifiers:
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* [[RXN-14396]]
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** 1 [[GLT]][c] '''+''' 1 [[ATP]][c] '''+''' 1 [[THF-GLU-N]][c] '''=>''' 1 [[THF-GLU-N]][c] '''+''' 1 [[ADP]][c] '''+''' 1 [[Pi]][c]
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== Reaction(s) of unknown directionality ==
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* With common name(s):
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* [[RXN-10642]]
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** 1 L-glutamate[c] '''+''' 1 ATP[c] '''+''' 1 a tetrahydrofolate[c] '''=>''' 1 a tetrahydrofolate[c] '''+''' 1 ADP[c] '''+''' 1 phosphate[c]
 +
 
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Tiso_gene_15942]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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* Gene: [[Tiso_gene_92]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[orthology-esiliculosus]]
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== Pathways  ==
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* [[PWY-2161]], folate polyglutamylation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2161 PWY-2161]
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** '''5''' reactions found over '''5''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-esiliculosus]]
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*** Tool: [[pantograph]]
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* Category: [[annotation]]
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** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* PUBCHEM:
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* LIGAND-RXN:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=25201940 25201940]
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** [http://www.genome.jp/dbget-bin/www_bget?R04241 R04241]
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* CHEMSPIDER:
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* UNIPROT:
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** [http://www.chemspider.com/Chemical-Structure.389644.html 389644]
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** [http://www.uniprot.org/uniprot/P15925 P15925]
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* CHEBI:
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** [http://www.uniprot.org/uniprot/Q9JVC6 Q9JVC6]
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=62626 62626]
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** [http://www.uniprot.org/uniprot/P43775 P43775]
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* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/Q9PNK6 Q9PNK6]
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** [http://www.genome.jp/dbget-bin/www_bget?C05766 C05766]
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** [http://www.uniprot.org/uniprot/Q9CGE0 Q9CGE0]
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* HMDB : HMDB02211
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** [http://www.uniprot.org/uniprot/Q50990 Q50990]
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{{#set: smiles=C(=O)([O-])CCC5(=C4(NC(CC1(NC(=C(CC([O-])=O)C(CCC(=O)[O-])=1)CC2(NC(=C(C(CCC(=O)[O-])=2)CC(=O)[O-])CC3(=C(CCC([O-])=O)C(CC(=O)[O-])=C(N3)C4))))=C(CC(=O)[O-])5))}}
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** [http://www.uniprot.org/uniprot/P48760 P48760]
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{{#set: inchi key=InChIKey=QTTNOSKSLATGQB-UHFFFAOYSA-F}}
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** [http://www.uniprot.org/uniprot/P08192 P08192]
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{{#set: common name=uroporphyrinogen-I}}
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** [http://www.uniprot.org/uniprot/O13492 O13492]
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{{#set: molecular weight=828.742    }}
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{{#set: direction=LEFT-TO-RIGHT}}
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{{#set: common name=uroporphyrinogen I}}
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{{#set: common name=folylpolyglutamate_synthase}}
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{{#set: produced by=RXN-14396}}
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{{#set: common name=bifunctional_protein}}
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{{#set: consumed or produced by=RXN-10642}}
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{{#set: ec number=EC-6.3.2.17}}
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{{#set: gene associated=Tiso_gene_15942|Tiso_gene_92}}
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{{#set: in pathway=PWY-2161}}
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{{#set: reconstruction category=orthology|annotation}}
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{{#set: reconstruction source=annotation-in-silico_annotation|orthology-esiliculosus}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:14, 21 March 2018

Reaction FOLYLPOLYGLUTAMATESYNTH-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • folylpolyglutamate_synthase
    • bifunctional_protein
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 L-glutamate[c] + 1 ATP[c] + 1 a tetrahydrofolate[c] => 1 a tetrahydrofolate[c] + 1 ADP[c] + 1 phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-2161, folate polyglutamylation: PWY-2161
    • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

External links





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