Difference between revisions of "RXN-9951"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=THMPT THMPT] == * smiles: ** CC([CH]1(C(C)NC2(=C(N1)C(NC(=N2)N)=O)))NC4(=CC=C(CC(C(C(COC3(C(C(C...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-9951 RXN-9951] == * direction: ** REVERSIBLE * common name: ** isocitrate dehydrogenase (NADP+)...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=THMPT THMPT] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-9951 RXN-9951] ==
* smiles:
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* direction:
** CC([CH]1(C(C)NC2(=C(N1)C(NC(=N2)N)=O)))NC4(=CC=C(CC(C(C(COC3(C(C(C(COP([O-])(=O)OC(C([O-])=O)CCC([O-])=O)O3)O)O))O)O)O)C=C4)
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** REVERSIBLE
* inchi key:
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** InChIKey=SCBIBGUJSMHIAI-LHIIQLEZSA-K
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* common name:
 
* common name:
** tetrahydromethanopterin
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** isocitrate dehydrogenase (NADP+)
* molecular weight:
+
** ORF
** 773.666   
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* Synonym(s):
 
* Synonym(s):
** THMPT
+
** oxalosuccinate decarboxylase
** 5,6,7,8-tetrahydromethanopterin
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** oxalsuccinic decarboxylase
** H4MPT
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** isocitrate (NADP) dehydrogenase
 +
** isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase
 +
** NADP-specific isocitrate dehydrogenase
 +
** NADP-linked isocitrate dehydrogenase
 +
** NADP isocitric dehydrogenase
 +
** isocitrate dehydrogenase (NADP-dependent)
 +
** NADP-dependent isocitric dehydrogenase
 +
** triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase
 +
** NADP+-linked isocitrate dehydrogenase
 +
** IDH (ambiguous)
 +
** dual-cofactor-specific isocitrate dehydrogenase
 +
** NADP+-ICDH
 +
** NADP+-IDH
 +
** IDP
 +
** IDP1
 +
** IDP2
 +
** IDP3
  
== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
== Reaction(s) known to produce the compound ==
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* With identifiers:
* [[RXN-15635]]
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** 1 [[THREO-DS-ISO-CITRATE]][c] '''+''' 1 [[NADP]][c] '''<=>''' 1 [[OXALO-SUCCINATE]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[NADPH]][c]
== Reaction(s) of unknown directionality ==
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* With common name(s):
 +
** 1 D-threo-isocitrate[c] '''+''' 1 NADP+[c] '''<=>''' 1 oxalosuccinate[c] '''+''' 1 H+[c] '''+''' 1 NADPH[c]
 +
 
 +
== Genes associated with this reaction  ==
 +
Genes have been associated with this reaction based on different elements listed below.
 +
* Gene: [[Tiso_gene_10809]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_18262]]
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-esiliculosus]]
 +
== Pathways  ==
 +
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-esiliculosus]]
 +
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Tool: [[pathwaytools]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
* PUBCHEM:
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* RHEA:
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=49791993 49791993]
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=25588 25588]
* CHEBI:
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* LIGAND-RXN:
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58103 58103]
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** [http://www.genome.jp/dbget-bin/www_bget?R01899 R01899]
* LIGAND-CPD:
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{{#set: direction=REVERSIBLE}}
** [http://www.genome.jp/dbget-bin/www_bget?C01217 C01217]
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{{#set: common name=isocitrate dehydrogenase (NADP+)}}
* HMDB : HMDB60403
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{{#set: common name=ORF}}
{{#set: smiles=CC([CH]1(C(C)NC2(=C(N1)C(NC(=N2)N)=O)))NC4(=CC=C(CC(C(C(COC3(C(C(C(COP([O-])(=O)OC(C([O-])=O)CCC([O-])=O)O3)O)O))O)O)O)C=C4)}}
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{{#set: common name=oxalosuccinate decarboxylase|oxalsuccinic decarboxylase|isocitrate (NADP) dehydrogenase|isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase|NADP-specific isocitrate dehydrogenase|NADP-linked isocitrate dehydrogenase|NADP isocitric dehydrogenase|isocitrate dehydrogenase (NADP-dependent)|NADP-dependent isocitric dehydrogenase|triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase|NADP+-linked isocitrate dehydrogenase|IDH (ambiguous)|dual-cofactor-specific isocitrate dehydrogenase|NADP+-ICDH|NADP+-IDH|IDP|IDP1|IDP2|IDP3}}
{{#set: inchi key=InChIKey=SCBIBGUJSMHIAI-LHIIQLEZSA-K}}
+
{{#set: gene associated=Tiso_gene_10809|Tiso_gene_18262}}
{{#set: common name=tetrahydromethanopterin}}
+
{{#set: in pathway=}}
{{#set: molecular weight=773.666    }}
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{{#set: reconstruction category=orthology|annotation}}
{{#set: common name=THMPT|5,6,7,8-tetrahydromethanopterin|H4MPT}}
+
{{#set: reconstruction source=annotation-experimental_annotation|annotation-in-silico_annotation|orthology-esiliculosus}}
{{#set: produced by=RXN-15635}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:14, 21 March 2018

Reaction RXN-9951

  • direction:
    • REVERSIBLE
  • common name:
    • isocitrate dehydrogenase (NADP+)
    • ORF
  • Synonym(s):
    • oxalosuccinate decarboxylase
    • oxalsuccinic decarboxylase
    • isocitrate (NADP) dehydrogenase
    • isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase
    • NADP-specific isocitrate dehydrogenase
    • NADP-linked isocitrate dehydrogenase
    • NADP isocitric dehydrogenase
    • isocitrate dehydrogenase (NADP-dependent)
    • NADP-dependent isocitric dehydrogenase
    • triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase
    • NADP+-linked isocitrate dehydrogenase
    • IDH (ambiguous)
    • dual-cofactor-specific isocitrate dehydrogenase
    • NADP+-ICDH
    • NADP+-IDH
    • IDP
    • IDP1
    • IDP2
    • IDP3

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

Reconstruction information

External links