Difference between revisions of "GMP-SYN-GLUT-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=ADP ADP] == * smiles: ** C(C3(C(C(C(N2(C1(=C(C(=NC=N1)N)N=C2)))O3)O)O))OP(OP(=O)([O-])[O-])([O-...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GMP-SYN-GLUT-RXN GMP-SYN-GLUT-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** glutamine_ami...")
 
(3 intermediate revisions by the same user not shown)
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[[Category:Metabolite]]
+
[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=ADP ADP] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GMP-SYN-GLUT-RXN GMP-SYN-GLUT-RXN] ==
* smiles:
+
* direction:
** C(C3(C(C(C(N2(C1(=C(C(=NC=N1)N)N=C2)))O3)O)O))OP(OP(=O)([O-])[O-])([O-])=O
+
** LEFT-TO-RIGHT
* inchi key:
+
** InChIKey=XTWYTFMLZFPYCI-KQYNXXCUSA-K
+
 
* common name:
 
* common name:
** ADP
+
** glutamine_amidotransferase
* molecular weight:
+
* ec number:
** 424.18   
+
** [http://enzyme.expasy.org/EC/6.3.5.2 EC-6.3.5.2]
 
* Synonym(s):
 
* Synonym(s):
** adenosine pyrophosphate
 
** adenosine 5'-pyrophosphate
 
** adenosine-5'-diphosphate
 
** adenosine-diphosphate
 
** adenosine-5-diphosphate
 
  
== Reaction(s) known to consume the compound ==
+
== Reaction Formula ==
* [[RXN-10862]]
+
* With identifiers:
* [[ADPREDUCT-RXN]]
+
** 1 [[GLN]][c] '''+''' 1 [[ATP]][c] '''+''' 1 [[WATER]][c] '''+''' 1 [[XANTHOSINE-5-PHOSPHATE]][c] '''=>''' 1 [[PPI]][c] '''+''' 1 [[GLT]][c] '''+''' 1 [[AMP]][c] '''+''' 1 [[GMP]][c] '''+''' 2 [[PROTON]][c]
* [[ADPA]]
+
* With common name(s):
* [[RXN-4305]]
+
** 1 L-glutamine[c] '''+''' 1 ATP[c] '''+''' 1 H2O[c] '''+''' 1 XMP[c] '''=>''' 1 diphosphate[c] '''+''' 1 L-glutamate[c] '''+''' 1 AMP[c] '''+''' 1 GMP[c] '''+''' 2 H+[c]
* [[ATP_3h_th]]
+
 
* [[ATP_3h_tm]]
+
== Genes associated with this reaction  ==
* [[RXN0-747]]
+
Genes have been associated with this reaction based on different elements listed below.
== Reaction(s) known to produce the compound ==
+
* Gene: [[Tiso_gene_6657]]
* [[ATPPH]]
+
** Source: [[annotation-in-silico_annotation]]
* [[DETHIOBIOTIN-SYN-RXN]]
+
*** Assignment: EC-NUMBER
* [[AGK]]
+
** Source: [[annotation-experimental_annotation]]
* [[SPHINGANINE-KINASE-RXN]]
+
*** Assignment: EC-NUMBER
* [[RXN-7913]]
+
** Source: [[orthology-athaliana]]
* [[BIS5-ADENOSYL-TRIPHOSPHATASE-RXN]]
+
** Source: [[orthology-synechocystis]]
* [[DEPHOSPHOCOAKIN-RXN]]
+
** Source: [[orthology-esiliculosus]]
* [[DGDPKIN-RXN]]
+
== Pathways  ==
* [[6.3.5.7-RXN]]
+
* [[PWY-7221]], guanosine ribonucleotides de novo biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7221 PWY-7221]
* [[3.6.3.1-RXN]]
+
** '''4''' reactions found over '''4''' reactions in the full pathway
* [[RXN-12093]]
+
== Reconstruction information  ==
* [[RXN-11109]]
+
* Category: [[orthology]]
* [[AUPT]]
+
** Source: [[orthology-athaliana]]
* [[RXN-8626]]
+
*** Tool: [[pantograph]]
* [[2.7.1.127-RXN]]
+
** Source: [[orthology-synechocystis]]
* [[PNKIN-RXN]]
+
*** Tool: [[pantograph]]
* [[XYLULOKIN-RXN]]
+
** Source: [[orthology-esiliculosus]]
* [[ARPT]]
+
*** Tool: [[pantograph]]
* [[GUANYL-KIN-RXN]]
+
* Category: [[manual]]
* [[ATCMf]]
+
** Source: [[manual-primary_network]]
* [[GLUTKIN-RXN]]
+
* Category: [[annotation]]
* [[ATDGM]]
+
** Source: [[annotation-experimental_annotation]]
* [[ATAM]]
+
*** Tool: [[pathwaytools]]
* [[DIHYDROFOLATESYNTH-RXN]]
+
** Source: [[annotation-in-silico_annotation]]
* [[RXN-7163]]
+
*** Tool: [[pathwaytools]]
* [[RXN66-521]]
+
* [[ATDGD]]
+
* [[HOMOSERKIN-RXN]]
+
* [[ATPASE-RXN]]
+
* [[RXN-1685]]
+
* [[TETRAACYLDISACC4KIN-RXN]]
+
* [[DGSNPT]]
+
* [[FRUCTOKINASE-RXN]]
+
* [[ADENYL-KIN-RXN]]
+
* [[GLUTAMINESYN-RXN]]
+
* [[ATID]]
+
* [[ATDTDm]]
+
* [[1-PHOSPHATIDYLINOSITOL-KINASE-RXN]]
+
* [[RXN1G-4355]]
+
* [[ATP_3h_th]]
+
* [[ATP_3h_tm]]
+
* [[PEPCARBOXYKIN-RXN]]
+
* [[FOLYLPOLYGLUTAMATESYNTH-RXN]]
+
* [[PYRUVATE-CARBOXYLASE-RXN]]
+
* [[RXN-12002]]
+
* [[ATCDm]]
+
* [[GLUTATHIONE-SYN-RXN]]
+
* [[ATDUD]]
+
* [[ACETYL-COA-CARBOXYLTRANSFER-RXN]]
+
* [[6.3.4.16-RXN]]
+
* [[RXN-15005]]
+
* [[6.3.5.6-RXN]]
+
* [[FORMATETHFLIG-RXN]]
+
* [[RXN1F-20]]
+
* [[ADENOSINETRIPHOSPHATASE-RXN]]
+
* [[PYRAMKIN-RXN]]
+
* [[ATDCDm]]
+
* [[PCr]]
+
* [[GLYRIBONUCSYN-RXN]]
+
* [[CTPSYN-RXN]]
+
* [[3.6.1.41-RXN]]
+
* [[DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN]]
+
* [[CHOLINE-KINASE-RXN]]
+
* [[DADPKIN-RXN]]
+
* [[NDPK]]
+
* [[RXN-14391]]
+
* [[RME256]]
+
* [[RME255]]
+
* [[ATCY]]
+
* [[ATCD]]
+
* [[CYTIKIN-RXN]]
+
* [[PYRIDOXKIN-RXN]]
+
* [[ATCM]]
+
* [[RXN3DJ-11417]]
+
* [[RXN0-742]]
+
* [[URIDINEKIN-RXN]]
+
* [[CARBPSYN-RXN]]
+
* [[3.6.4.9-RXN]]
+
* [[KETOHEXOKINASE-RXN]]
+
* [[RXN0-4261]]
+
* [[DCDPKIN-RXN]]
+
* [[SAICARSYN-RXN]]
+
* [[GLUTCYSLIG-RXN]]
+
* [[2.7.13.3-RXN]]
+
* [[3.6.4.1-RXN]]
+
* [[RXN-14325]]
+
* [[5-OXOPROLINASE-ATP-HYDROLYSING-RXN]]
+
* [[RXN-14074]]
+
* [[2.7.1.68-RXN]]
+
* [[AGPT]]
+
* [[PROTEIN-KINASE-RXN]]
+
* [[DTDPKIN-RXN]]
+
* [[GLUCURONOKINASE-RXN]]
+
* [[FORMYLTHFGLUSYNTH-RXN]]
+
* [[FA160COAabcp]]
+
* [[UDPGtni]]
+
* [[PYRIMSYN3-RXN]]
+
* [[NUCLEOSIDE-PHOSPHATE-KINASE-RXN]]
+
* [[THMPPPT]]
+
* [[3.6.3.50-RXN]]
+
* [[CDPKIN-RXN]]
+
* [[6.3.2.25-RXN]]
+
* [[THIAZOLSYN3-RXN]]
+
* [[RME144]]
+
* [[ATUDm]]
+
* [[3.6.4.6-RXN]]
+
* [[METHYLCROTONYL-COA-CARBOXYLASE-RXN]]
+
* [[MANNKIN-RXN]]
+
* [[RXN0-5055]]
+
* [[GLY3KIN-RXN]]
+
* [[UDPKIN-RXN]]
+
* [[ATDCD]]
+
* [[ATDTD]]
+
* [[ATDCMf]]
+
* [[ATIDm]]
+
* [[DCYTPT]]
+
* [[PANTOTHENATE-KIN-RXN]]
+
* [[DUDPKIN-RXN]]
+
* [[2.7.1.140-RXN]]
+
* [[AIRS-RXN]]
+
* [[RXN0-5116]]
+
* [[DIACYLGLYKIN-RXN]]
+
* [[ATAMf]]
+
* [[2.7.1.139-RXN]]
+
* [[AGPTf]]
+
* [[ADENOSINE-KINASE-RXN]]
+
* [[DTMPKI-RXN]]
+
* [[ATAMm]]
+
* [[M5TRK]]
+
* [[ATUD]]
+
* [[2.7.1.134-RXN]]
+
* [[RIBOKIN-RXN]]
+
* [[2.7.1.133-RXN]]
+
* [[ATDUDm]]
+
* [[BIOTIN-CARBOXYL-RXN]]
+
* [[RXN0-6541]]
+
* [[RXN0-1401]]
+
* [[RXN-14196]]
+
* [[FTHFL]]
+
* [[2.7.1.149-RXN]]
+
* [[RIBOFLAVINKIN-RXN]]
+
* [[NAD-KIN-RXN]]
+
* [[GLYCERONE-KINASE-RXN]]
+
* [[GDPKIN-RXN]]
+
* [[ADCPT]]
+
* [[AASP]]
+
* [[RXN-13202]]
+
* [[THIAMIN-DIPHOSPHATE-KINASE-RXN]]
+
* [[ATDCM]]
+
* [[2.7.10.1-RXN]]
+
* [[RXN-11832]]
+
* [[2.7.1.148-RXN]]
+
* [[ETHANOLAMINE-KINASE-RXN]]
+
* [[ATGD]]
+
* [[RXN-16909]]
+
* [[6-PHOSPHOFRUCTO-2-KINASE-RXN]]
+
* [[ATDAM]]
+
* [[DAD2PT]]
+
* [[GLCURK]]
+
* [[NUCLEOSIDE-DIP-KIN-RXN]]
+
* [[GMKALT-RXN]]
+
* [[3.6.4.4-RXN]]
+
* [[PE1819Z1819Zt]]
+
* [[NDPKm]]
+
* [[DEOXYADENYLATE-KINASE-RXN]]
+
* [[RXN-8443]]
+
* [[RME294]]
+
* [[6PFRUCTPHOS-RXN]]
+
* [[UMPKf]]
+
* [[CARNOSINE-SYNTHASE-RXN]]
+
* [[GLUCOKIN-RXN]]
+
* [[RXN0-2921]]
+
* [[FGAMSYN-RXN]]
+
== Reaction(s) of unknown directionality ==
+
* [[2.7.11.2-RXN]]
+
* [[GALACTOKIN-RXN]]
+
* [[HEXOKINASE-RXN]]
+
* [[RXN-6341]]
+
* [[5.99.1.3-RXN]]
+
* [[RXN-14906]]
+
* [[SHIKIMATE-KINASE-RXN]]
+
* [[ASPARTATEKIN-RXN]]
+
* [[PROPIONYL-COA-CARBOXY-RXN]]
+
* [[3.6.3.8-RXN]]
+
* [[PHOSPHORIBULOKINASE-RXN]]
+
* [[ADENYLYLSULFKIN-RXN]]
+
* [[GLYCEROL-KIN-RXN]]
+
* [[ACETYLGLUTKIN-RXN]]
+
* [[TRANS-RXN-249]]
+
* [[PEPDEPHOS-RXN]]
+
* [[TAU-PROTEIN-KINASE-RXN]]
+
* [[RXN-14120]]
+
* [[CARBAMATE-KINASE-RXN]]
+
* [[2.7.12.2-RXN]]
+
* [[2.4.1.213-RXN]]
+
* [[RXN-16317]]
+
* [[RXN-11135]]
+
* [[RXN-10038]]
+
* [[MEVALONATE-KINASE-RXN]]
+
* [[2.7.11.20-RXN]]
+
* [[2.7.12.1-RXN]]
+
* [[2.7.11.24-RXN]]
+
* [[D-RIBULOKIN-RXN]]
+
* [[PANTETHEINE-KINASE-RXN]]
+
* [[2.7.11.18-RXN]]
+
* [[PROLINE-MULTI]]
+
* [[ATPSYN-RXN]]
+
* [[RXN-14223]]
+
* [[SUCCCOASYN-RXN]]
+
* [[RIBULOKIN-RXN]]
+
* [[RXN-14228]]
+
* [[PHOSGLYPHOS-RXN]]
+
* [[2.7.11.22-RXN]]
+
 
== External links  ==
 
== External links  ==
* CAS : 58-64-0
+
* RHEA:
* METABOLIGHTS : MTBLC456216
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=11680 11680]
* PUBCHEM:
+
* LIGAND-RXN:
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=7058055 7058055]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01231 R01231]
* HMDB : HMDB01341
+
* UNIPROT:
* LIGAND-CPD:
+
** [http://www.uniprot.org/uniprot/P32073 P32073]
** [http://www.genome.jp/dbget-bin/www_bget?C00008 C00008]
+
** [http://www.uniprot.org/uniprot/P49915 P49915]
* CHEMSPIDER:
+
** [http://www.uniprot.org/uniprot/O25165 O25165]
** [http://www.chemspider.com/Chemical-Structure.5414423.html 5414423]
+
** [http://www.uniprot.org/uniprot/Q58531 Q58531]
* CHEBI:
+
** [http://www.uniprot.org/uniprot/Q9PN49 Q9PN49]
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=456216 456216]
+
** [http://www.uniprot.org/uniprot/P29727 P29727]
* BIGG : adp
+
** [http://www.uniprot.org/uniprot/O66601 O66601]
{{#set: smiles=C(C3(C(C(C(N2(C1(=C(C(=NC=N1)N)N=C2)))O3)O)O))OP(OP(=O)([O-])[O-])([O-])=O}}
+
** [http://www.uniprot.org/uniprot/P49056 P49056]
{{#set: inchi key=InChIKey=XTWYTFMLZFPYCI-KQYNXXCUSA-K}}
+
** [http://www.uniprot.org/uniprot/Q9CFJ0 Q9CFJ0]
{{#set: common name=ADP}}
+
** [http://www.uniprot.org/uniprot/Q9JW60 Q9JW60]
{{#set: molecular weight=424.18    }}
+
** [http://www.uniprot.org/uniprot/P44335 P44335]
{{#set: common name=adenosine pyrophosphate|adenosine 5'-pyrophosphate|adenosine-5'-diphosphate|adenosine-diphosphate|adenosine-5-diphosphate}}
+
** [http://www.uniprot.org/uniprot/P38625 P38625]
{{#set: consumed by=RXN-10862|ADPREDUCT-RXN|ADPA|RXN-4305|ATP_3h_th|ATP_3h_tm|RXN0-747}}
+
** [http://www.uniprot.org/uniprot/P49057 P49057]
{{#set: produced by=ATPPH|DETHIOBIOTIN-SYN-RXN|AGK|SPHINGANINE-KINASE-RXN|RXN-7913|BIS5-ADENOSYL-TRIPHOSPHATASE-RXN|DEPHOSPHOCOAKIN-RXN|DGDPKIN-RXN|6.3.5.7-RXN|3.6.3.1-RXN|RXN-12093|RXN-11109|AUPT|RXN-8626|2.7.1.127-RXN|PNKIN-RXN|XYLULOKIN-RXN|ARPT|GUANYL-KIN-RXN|ATCMf|GLUTKIN-RXN|ATDGM|ATAM|DIHYDROFOLATESYNTH-RXN|RXN-7163|RXN66-521|ATDGD|HOMOSERKIN-RXN|ATPASE-RXN|RXN-1685|TETRAACYLDISACC4KIN-RXN|DGSNPT|FRUCTOKINASE-RXN|ADENYL-KIN-RXN|GLUTAMINESYN-RXN|ATID|ATDTDm|1-PHOSPHATIDYLINOSITOL-KINASE-RXN|RXN1G-4355|ATP_3h_th|ATP_3h_tm|PEPCARBOXYKIN-RXN|FOLYLPOLYGLUTAMATESYNTH-RXN|PYRUVATE-CARBOXYLASE-RXN|RXN-12002|ATCDm|GLUTATHIONE-SYN-RXN|ATDUD|ACETYL-COA-CARBOXYLTRANSFER-RXN|6.3.4.16-RXN|RXN-15005|6.3.5.6-RXN|FORMATETHFLIG-RXN|RXN1F-20|ADENOSINETRIPHOSPHATASE-RXN|PYRAMKIN-RXN|ATDCDm|PCr|GLYRIBONUCSYN-RXN|CTPSYN-RXN|3.6.1.41-RXN|DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN|CHOLINE-KINASE-RXN|DADPKIN-RXN|NDPK|RXN-14391|RME256|RME255|ATCY|ATCD|CYTIKIN-RXN|PYRIDOXKIN-RXN|ATCM|RXN3DJ-11417|RXN0-742|URIDINEKIN-RXN|CARBPSYN-RXN|3.6.4.9-RXN|KETOHEXOKINASE-RXN|RXN0-4261|DCDPKIN-RXN|SAICARSYN-RXN|GLUTCYSLIG-RXN|2.7.13.3-RXN|3.6.4.1-RXN|RXN-14325|5-OXOPROLINASE-ATP-HYDROLYSING-RXN|RXN-14074|2.7.1.68-RXN|AGPT|PROTEIN-KINASE-RXN|DTDPKIN-RXN|GLUCURONOKINASE-RXN|FORMYLTHFGLUSYNTH-RXN|FA160COAabcp|UDPGtni|PYRIMSYN3-RXN|NUCLEOSIDE-PHOSPHATE-KINASE-RXN|THMPPPT|3.6.3.50-RXN|CDPKIN-RXN|6.3.2.25-RXN|THIAZOLSYN3-RXN|RME144|ATUDm|3.6.4.6-RXN|METHYLCROTONYL-COA-CARBOXYLASE-RXN|MANNKIN-RXN|RXN0-5055|GLY3KIN-RXN|UDPKIN-RXN|ATDCD|ATDTD|ATDCMf|ATIDm|DCYTPT|PANTOTHENATE-KIN-RXN|DUDPKIN-RXN|2.7.1.140-RXN|AIRS-RXN|RXN0-5116|DIACYLGLYKIN-RXN|ATAMf|2.7.1.139-RXN|AGPTf|ADENOSINE-KINASE-RXN|DTMPKI-RXN|ATAMm|M5TRK|ATUD|2.7.1.134-RXN|RIBOKIN-RXN|2.7.1.133-RXN|ATDUDm|BIOTIN-CARBOXYL-RXN|RXN0-6541|RXN0-1401|RXN-14196|FTHFL|2.7.1.149-RXN|RIBOFLAVINKIN-RXN|NAD-KIN-RXN|GLYCERONE-KINASE-RXN|GDPKIN-RXN|ADCPT|AASP|RXN-13202|THIAMIN-DIPHOSPHATE-KINASE-RXN|ATDCM|2.7.10.1-RXN|RXN-11832|2.7.1.148-RXN|ETHANOLAMINE-KINASE-RXN|ATGD|RXN-16909|6-PHOSPHOFRUCTO-2-KINASE-RXN|ATDAM|DAD2PT|GLCURK|NUCLEOSIDE-DIP-KIN-RXN|GMKALT-RXN|3.6.4.4-RXN|PE1819Z1819Zt|NDPKm|DEOXYADENYLATE-KINASE-RXN|RXN-8443|RME294|6PFRUCTPHOS-RXN|UMPKf|CARNOSINE-SYNTHASE-RXN|GLUCOKIN-RXN|RXN0-2921|FGAMSYN-RXN}}
+
** [http://www.uniprot.org/uniprot/P04079 P04079]
{{#set: consumed or produced by=2.7.11.2-RXN|GALACTOKIN-RXN|HEXOKINASE-RXN|RXN-6341|5.99.1.3-RXN|RXN-14906|SHIKIMATE-KINASE-RXN|ASPARTATEKIN-RXN|PROPIONYL-COA-CARBOXY-RXN|3.6.3.8-RXN|PHOSPHORIBULOKINASE-RXN|ADENYLYLSULFKIN-RXN|GLYCEROL-KIN-RXN|ACETYLGLUTKIN-RXN|TRANS-RXN-249|PEPDEPHOS-RXN|TAU-PROTEIN-KINASE-RXN|RXN-14120|CARBAMATE-KINASE-RXN|2.7.12.2-RXN|2.4.1.213-RXN|RXN-16317|RXN-11135|RXN-10038|MEVALONATE-KINASE-RXN|2.7.11.20-RXN|2.7.12.1-RXN|2.7.11.24-RXN|D-RIBULOKIN-RXN|PANTETHEINE-KINASE-RXN|2.7.11.18-RXN|PROLINE-MULTI|ATPSYN-RXN|RXN-14223|SUCCCOASYN-RXN|RIBULOKIN-RXN|RXN-14228|PHOSGLYPHOS-RXN|2.7.11.22-RXN}}
+
** [http://www.uniprot.org/uniprot/Q7VLE9 Q7VLE9]
 +
{{#set: direction=LEFT-TO-RIGHT}}
 +
{{#set: common name=glutamine_amidotransferase}}
 +
{{#set: ec number=EC-6.3.5.2}}
 +
{{#set: gene associated=Tiso_gene_6657}}
 +
{{#set: in pathway=PWY-7221}}
 +
{{#set: reconstruction category=orthology|manual|annotation}}
 +
{{#set: reconstruction source=annotation-experimental_annotation|orthology-esiliculosus|annotation-in-silico_annotation|orthology-athaliana|orthology-synechocystis|manual-primary_network}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:18, 21 March 2018

Reaction GMP-SYN-GLUT-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • glutamine_amidotransferase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 L-glutamine[c] + 1 ATP[c] + 1 H2O[c] + 1 XMP[c] => 1 diphosphate[c] + 1 L-glutamate[c] + 1 AMP[c] + 1 GMP[c] + 2 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-7221, guanosine ribonucleotides de novo biosynthesis: PWY-7221
    • 4 reactions found over 4 reactions in the full pathway

Reconstruction information

External links