Difference between revisions of "RXN3DJ-11417"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.2.4.4-RXN 1.2.4.4-RXN] == * direction: ** REVERSIBLE * common name: ** 3-methyl-2-oxobutanoate_de...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN3DJ-11417 RXN3DJ-11417] == * direction: ** LEFT-TO-RIGHT * common name: ** sphingosine_kinase_1...")
 
(3 intermediate revisions by the same user not shown)
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.2.4.4-RXN 1.2.4.4-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN3DJ-11417 RXN3DJ-11417] ==
 
* direction:
 
* direction:
−
** REVERSIBLE
+
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
−
** 3-methyl-2-oxobutanoate_dehydrogenase
+
** sphingosine_kinase_1
−
** 2-oxoisovalerate_dehydrogenase_alpha_subunit_mitochondrial
+
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/1.2.4.4 EC-1.2.4.4]
+
** [http://enzyme.expasy.org/EC/2.7.1.91 EC-2.7.1.91]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[PROTON]][c] '''+''' 1 [[2-KETO-ISOVALERATE]][c] '''+''' 1 [[BCAA-dehydrogenase-lipoyl]][c] '''<=>''' 1 [[BCAA-dehydrogenase-2MP-DH-lipoyl]][c] '''+''' 1 [[CARBON-DIOXIDE]][c]
+
** 1 [[SPHINGOSINE]][c] '''+''' 1 [[ATP]][c] '''=>''' 1 [[CPD3DJ-11366]][c] '''+''' 1 [[ADP]][c] '''+''' 1 [[PROTON]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 H+[c] '''+''' 1 3-methyl-2-oxobutanoate[c] '''+''' 1 an [apo BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] '''<=>''' 1 an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylpropanoyl]dihydrolipoyl-L-lysine[c] '''+''' 1 CO2[c]
+
** 1 sphingosine[c] '''+''' 1 ATP[c] '''=>''' 1 sphingosine 1-phosphate[c] '''+''' 1 ADP[c] '''+''' 1 H+[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[Tiso_gene_18084]]
+
* Gene: [[Tiso_gene_1163]]
−
** [[pantograph]]-[[esiliculosus]]
+
** Source: [[annotation-in-silico_annotation]]
−
* [[Tiso_gene_11793]]
+
*** Assignment: AUTOMATED-NAME-MATCH
−
** IN-SILICO_ANNOTATION
+
−
***AUTOMATED-NAME-MATCH
+
−
* [[Tiso_gene_3260]]
+
−
** IN-SILICO_ANNOTATION
+
−
***EC-NUMBER
+
−
** EXPERIMENTAL_ANNOTATION
+
−
***EC-NUMBER
+
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-5046]], 2-oxoisovalerate decarboxylation to isobutanoyl-CoA: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5046 PWY-5046]
+
* [[PWY3DJ-11470]], sphingosine and sphingosine-1-phosphate metabolism: [http://metacyc.org/META/NEW-IMAGE?object=PWY3DJ-11470 PWY3DJ-11470]
−
** '''3''' reactions found over '''3''' reactions in the full pathway
+
** '''3''' reactions found over '''5''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* [[orthology]]:
+
* Category: [[annotation]]
−
** [[pantograph]]:
+
** Source: [[annotation-in-silico_annotation]]
−
*** [[esiliculosus]]
+
*** Tool: [[pathwaytools]]
−
* [[annotation]]:
+
−
** [[pathwaytools]]:
+
−
*** [[experimental_annotation]]
+
−
*** [[in-silico_annotation]]
+
 
== External links  ==
 
== External links  ==
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R01701 R01701]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01926 R01926]
−
* UNIPROT:
+
{{#set: direction=LEFT-TO-RIGHT}}
−
** [http://www.uniprot.org/uniprot/P21839 P21839]
+
{{#set: common name=sphingosine_kinase_1}}
−
** [http://www.uniprot.org/uniprot/P21953 P21953]
+
{{#set: ec number=EC-2.7.1.91}}
−
** [http://www.uniprot.org/uniprot/P37940 P37940]
+
{{#set: gene associated=Tiso_gene_1163}}
−
** [http://www.uniprot.org/uniprot/Q9PK54 Q9PK54]
+
{{#set: in pathway=PWY3DJ-11470}}
−
** [http://www.uniprot.org/uniprot/P37941 P37941]
+
−
** [http://www.uniprot.org/uniprot/P11178 P11178]
+
−
** [http://www.uniprot.org/uniprot/P12694 P12694]
+
−
** [http://www.uniprot.org/uniprot/P09061 P09061]
+
−
** [http://www.uniprot.org/uniprot/P09060 P09060]
+
−
** [http://www.uniprot.org/uniprot/P11960 P11960]
+
−
** [http://www.uniprot.org/uniprot/O84344 O84344]
+
−
** [http://www.uniprot.org/uniprot/Q9Z9E8 Q9Z9E8]
+
−
** [http://www.uniprot.org/uniprot/Q9I1M2 Q9I1M2]
+
−
** [http://www.uniprot.org/uniprot/P35738 P35738]
+
−
** [http://www.uniprot.org/uniprot/P50136 P50136]
+
−
** [http://www.uniprot.org/uniprot/O48615 O48615]
+
−
** [http://www.uniprot.org/uniprot/O03849 O03849]
+
−
** [http://www.uniprot.org/uniprot/Q53592 Q53592]
+
−
** [http://www.uniprot.org/uniprot/Q53593 Q53593]
+
−
** [http://www.uniprot.org/uniprot/O82450 O82450]
+
−
{{#set: direction=REVERSIBLE}}
+
−
{{#set: common name=3-methyl-2-oxobutanoate_dehydrogenase}}
+
−
{{#set: common name=2-oxoisovalerate_dehydrogenase_alpha_subunit_mitochondrial}}
+
−
{{#set: ec number=EC-1.2.4.4}}
+
−
{{#set: gene associated=Tiso_gene_18084|Tiso_gene_11793|Tiso_gene_3260}}
+
−
{{#set: in pathway=PWY-5046}}
+
−
{{#set: reconstruction category=orthology}}
+
−
{{#set: reconstruction tool=pantograph}}
+
−
{{#set: reconstruction source=esiliculosus}}
+
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 +
{{#set: reconstruction source=annotation-in-silico_annotation}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}
−
{{#set: reconstruction source=experimental_annotation|in-silico_annotation}}
 

Latest revision as of 20:20, 21 March 2018

Reaction RXN3DJ-11417

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • sphingosine_kinase_1
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 sphingosine[c] + 1 ATP[c] => 1 sphingosine 1-phosphate[c] + 1 ADP[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY3DJ-11470, sphingosine and sphingosine-1-phosphate metabolism: PWY3DJ-11470
    • 3 reactions found over 5 reactions in the full pathway

Reconstruction information

External links





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