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| [[Category:Reaction]] | | [[Category:Reaction]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=ACETOOHBUTSYN-RXN ACETOOHBUTSYN-RXN] == | + | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RME297 RME297] == |
| * direction: | | * direction: |
− | ** LEFT-TO-RIGHT | + | ** REVERSIBLE |
| * common name: | | * common name: |
− | ** 2-aceto-2-hydroxy-butyrate synthase | + | ** RME297 |
− | ** Acetolactate synthase catalytic subunit, mitochondrial
| + | |
− | * ec number:
| + | |
− | ** [http://enzyme.expasy.org/EC/2.2.1.6 EC-2.2.1.6]
| + | |
| * Synonym(s): | | * Synonym(s): |
| | | |
| == Reaction Formula == | | == Reaction Formula == |
| * With identifiers: | | * With identifiers: |
− | ** 1 [[PYRUVATE]][c] '''+''' 1 [[2-OXOBUTANOATE]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[2-ACETO-2-HYDROXY-BUTYRATE]][c] | + | ** 1.0 [[NADH-P-OR-NOP]][c] '''<=>''' 1.0 [[NADH]][c] |
| * With common name(s): | | * With common name(s): |
− | ** 1 pyruvate[c] '''+''' 1 2-oxobutanoate[c] '''+''' 1 H+[c] '''=>''' 1 CO2[c] '''+''' 1 (S)-2-aceto-2-hydroxybutanoate[c] | + | ** 1.0 NAD(P)H[c] '''<=>''' 1.0 NADH[c] |
| | | |
| == Genes associated with this reaction == | | == Genes associated with this reaction == |
− | Genes have been associated with this reaction based on different elements listed below.
| |
− | * [[Tiso_gene_11362]]
| |
− | ** EXPERIMENTAL_ANNOTATION
| |
− | ***EC-NUMBER
| |
| == Pathways == | | == Pathways == |
− | * [[PWY-5103]], L-isoleucine biosynthesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5103 PWY-5103]
| |
− | ** '''4''' reactions found over '''7''' reactions in the full pathway
| |
− | * [[ILEUSYN-PWY]], L-isoleucine biosynthesis I (from threonine): [http://metacyc.org/META/NEW-IMAGE?object=ILEUSYN-PWY ILEUSYN-PWY]
| |
− | ** '''7''' reactions found over '''7''' reactions in the full pathway
| |
− | * [[PWY-5101]], L-isoleucine biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5101 PWY-5101]
| |
− | ** '''5''' reactions found over '''8''' reactions in the full pathway
| |
− | * [[PWY-5104]], L-isoleucine biosynthesis IV: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5104 PWY-5104]
| |
− | ** '''3''' reactions found over '''6''' reactions in the full pathway
| |
| == Reconstruction information == | | == Reconstruction information == |
− | * [[manual]]: | + | * Category: [[manual]] |
− | ** [[primary_network]] | + | ** Source: [[manual-primary_network]] |
− | * [[annotation]]:
| + | |
− | ** [[pathwaytools]]:
| + | |
− | *** [[experimental_annotation]]
| + | |
| == External links == | | == External links == |
− | * RHEA:
| + | {{#set: direction=REVERSIBLE}} |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=27654 27654]
| + | {{#set: common name=RME297}} |
− | * LIGAND-RXN:
| + | {{#set: in pathway=}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R08648 R08648]
| + | |
− | * UNIPROT:
| + | |
− | ** [http://www.uniprot.org/uniprot/Q59950 Q59950]
| + | |
− | ** [http://www.uniprot.org/uniprot/P42463 P42463]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q8XAV3 Q8XAV3]
| + | |
− | ** [http://www.uniprot.org/uniprot/P27868 P27868]
| + | |
− | ** [http://www.uniprot.org/uniprot/P45260 P45260]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q57625 Q57625]
| + | |
− | ** [http://www.uniprot.org/uniprot/P37251 P37251]
| + | |
− | ** [http://www.uniprot.org/uniprot/P45261 P45261]
| + | |
− | ** [http://www.uniprot.org/uniprot/O27493 O27493]
| + | |
− | ** [http://www.uniprot.org/uniprot/O66759 O66759]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9PHU2 Q9PHU2]
| + | |
− | ** [http://www.uniprot.org/uniprot/O05031 O05031]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q57725 Q57725]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9PHU1 Q9PHU1]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9JTI1 Q9JTI1]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q58077 Q58077]
| + | |
− | ** [http://www.uniprot.org/uniprot/O28554 O28554]
| + | |
− | ** [http://www.uniprot.org/uniprot/O53554 O53554]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q04789 Q04789]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9JRF4 Q9JRF4]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q59272 Q59272]
| + | |
− | ** [http://www.uniprot.org/uniprot/P27696 P27696]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q59498 Q59498]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9RFQ7 Q9RFQ7]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q05767 Q05767]
| + | |
− | ** [http://www.uniprot.org/uniprot/P40811 P40811]
| + | |
− | ** [http://www.uniprot.org/uniprot/P21622 P21622]
| + | |
− | ** [http://www.uniprot.org/uniprot/P27818 P27818]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q41768 Q41768]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q41769 Q41769]
| + | |
− | ** [http://www.uniprot.org/uniprot/P69684 P69684]
| + | |
− | ** [http://www.uniprot.org/uniprot/P27819 P27819]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9R586 Q9R586]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q02137 Q02137]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q02140 Q02140]
| + | |
− | ** [http://www.uniprot.org/uniprot/P36620 P36620]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q42767 Q42767]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q42768 Q42768]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q49865 Q49865]
| + | |
− | ** [http://www.uniprot.org/uniprot/O22547 O22547]
| + | |
− | ** [http://www.uniprot.org/uniprot/O49229 O49229]
| + | |
− | ** [http://www.uniprot.org/uniprot/O22578 O22578]
| + | |
− | ** [http://www.uniprot.org/uniprot/O49210 O49210]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q60021 Q60021]
| + | |
− | ** [http://www.uniprot.org/uniprot/P07342 P07342]
| + | |
− | ** [http://www.uniprot.org/uniprot/P00892 P00892]
| + | |
− | ** [http://www.uniprot.org/uniprot/P08142 P08142]
| + | |
− | ** [http://www.uniprot.org/uniprot/P0ADF8 P0ADF8]
| + | |
− | ** [http://www.uniprot.org/uniprot/P00894 P00894]
| + | |
− | ** [http://www.uniprot.org/uniprot/P00893 P00893]
| + | |
− | ** [http://www.uniprot.org/uniprot/P17597 P17597]
| + | |
− | ** [http://www.uniprot.org/uniprot/P09342 P09342]
| + | |
− | ** [http://www.uniprot.org/uniprot/P09114 P09114]
| + | |
− | ** [http://www.uniprot.org/uniprot/P14874 P14874]
| + | |
− | {{#set: direction=LEFT-TO-RIGHT}} | + | |
− | {{#set: common name=2-aceto-2-hydroxy-butyrate synthase}} | + | |
− | {{#set: common name=Acetolactate synthase catalytic subunit, mitochondrial}}
| + | |
− | {{#set: ec number=EC-2.2.1.6}}
| + | |
− | {{#set: gene associated=Tiso_gene_11362}}
| + | |
− | {{#set: in pathway=PWY-5103|ILEUSYN-PWY|PWY-5101|PWY-5104}} | + | |
| {{#set: reconstruction category=manual}} | | {{#set: reconstruction category=manual}} |
− | {{#set: reconstruction source=primary_network}} | + | {{#set: reconstruction source=manual-primary_network}} |
− | {{#set: reconstruction category=annotation}}
| + | |
− | {{#set: reconstruction tool=pathwaytools}}
| + | |
− | {{#set: reconstruction source=experimental_annotation}}
| + | |