RXN-14116

Reaction RXN-14116

• direction:
  • LEFT-TO-RIGHT
• common name:
  • ORF
  • delta-1-pyrroline-5-carboxylate_synthase
  • delta-1-pyrroline-5-carboxylate_dehydrogenase_mitochondrial
• ec number:
  • EC-1.2.1.88
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 WATER[c] + 1 L-GLUTAMATE_GAMMA-SEMIALDEHYDE[c] + 1 NAD[c] => 2 PROTON[c] + 1 NADH[c] + 1 GLT[c]
• With common name(s):
  • 1 H2O[c] + 1 L-glutamate-5-semialdehyde[c] + 1 NAD+[c] => 2 H+[c] + 1 NADH[c] + 1 L-glutamate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_6952
  • Source: orthology-synechocystis
• Gene: Tiso_gene_3513
  • Source: orthology-synechocystis
• Gene: Tiso_gene_7381
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_16634
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_18338
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_886
  • Source: orthology-synechocystis
• Gene: Tiso_gene_9680
  • Source: orthology-synechocystis
• Gene: Tiso_gene_18337
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER

Pathways

• PROUT-PWY, L-proline degradation: PROUT-PWY
  • 3 reactions found over 3 reactions in the full pathway
• ARGASEDEG-PWY, L-arginine degradation I (arginase pathway): ARGASEDEG-PWY
  • 3 reactions found over 3 reactions in the full pathway
• PWY-6853, ethylene biosynthesis II (microbes): PWY-6853
  • 2 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-synechocystis
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 30236
• LIGAND-RXN:
  • R00245