4.2.1.61-RXN

Reaction 4.2.1.61-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • polyketide_synthase
• ec number:
  • EC-2.3.1.86
  • EC-2.3.1.85
  • EC-4.2.1.59
• Synonym(s):
  • D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase
  • β-hydroxypalmitoyl-acyl carrier protein dehydrase
  • β-hydroxypalmitoyl thioester dehydratase
  • β-hydroxypalmityl-ACP dehydrase
  • (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase
  • (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase (hexadec-2-enoyl-[acyl-carrier protein]-forming)

Reaction Formula

• With identifiers:
  • 1 R-3-Hydroxypalmitoyl-ACPs[c] => 1 2-Hexadecenoyl-ACPs[c] + 1 WATER[c]
• With common name(s):
  • 1 a (3R)-3-hydroxypalmitoyl-[acp][c] => 1 a trans hexadecenoyl-[acp][c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_136
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_13394
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_6884
  • Source: annotation-experimental_annotation
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: Tiso_gene_135
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_500
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_10876
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER

Pathways

• PWY-5971, palmitate biosynthesis II (bacteria and plants): PWY-5971
  • 31 reactions found over 31 reactions in the full pathway
• PWY-5994, palmitate biosynthesis I (animals and fungi): PWY-5994
  • 31 reactions found over 31 reactions in the full pathway

Reconstruction information

• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R04462
• UNIPROT:
  • P49327
  • P07149
  • P12276
  • P12785

• "D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase" cannot be used as a page name in this wiki.
• "(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase" cannot be used as a page name in this wiki.
• "(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase (hexadec-2-enoyl-[acyl-carrier protein]-forming)" cannot be used as a page name in this wiki.