RXN-12376

Reaction RXN-12376

• direction:
  • LEFT-TO-RIGHT
• common name:
  • trna_(guanine_-n1)-methyltransferase
  • probable_trna_(guanine_-n_)-dimethyltransferase_1
• ec number:
  • EC-2.1.1.216
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 tRNA-Containing-N2-Methylguanine-26[c] + 1 S-ADENOSYLMETHIONINE[c] => 1 tRNA-Containing-N2-dimethylguanine-26[c] + 1 ADENOSYL-HOMO-CYS[c] + 1 PROTON[c]
• With common name(s):
  • 1 an N2-methylguanine26 in tRNA[c] + 1 S-adenosyl-L-methionine[c] => 1 an N2dimethylguanine26 in tRNA[c] + 1 S-adenosyl-L-homocysteine[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_9360
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_16307
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER

Pathways

• PWY-6829, tRNA methylation (yeast): PWY-6829
  • 3 reactions found over 15 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools