RXN-9951

Reaction RXN-9951

• direction:
  • REVERSIBLE
• common name:
  • isocitrate dehydrogenase (NADP+)
  • ORF
• Synonym(s):
  • oxalosuccinate decarboxylase
  • oxalsuccinic decarboxylase
  • isocitrate (NADP) dehydrogenase
  • isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase
  • NADP-specific isocitrate dehydrogenase
  • NADP-linked isocitrate dehydrogenase
  • NADP isocitric dehydrogenase
  • isocitrate dehydrogenase (NADP-dependent)
  • NADP-dependent isocitric dehydrogenase
  • triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase
  • NADP+-linked isocitrate dehydrogenase
  • IDH (ambiguous)
  • dual-cofactor-specific isocitrate dehydrogenase
  • NADP+-ICDH
  • NADP+-IDH
  • IDP
  • IDP1
  • IDP2
  • IDP3

Reaction Formula

• With identifiers:
  • 1 THREO-DS-ISO-CITRATE[c] + 1 NADP[c] <=> 1 OXALO-SUCCINATE[c] + 1 PROTON[c] + 1 NADPH[c]
• With common name(s):
  • 1 D-threo-isocitrate[c] + 1 NADP+[c] <=> 1 oxalosuccinate[c] + 1 H+[c] + 1 NADPH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_10809
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_18262
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 25588
• LIGAND-RXN:
  • R01899