CO+2

Reaction 2.3.1.168-RXN

• direction:
  • REVERSIBLE
• common name:
  • 3-methyl-2-oxobutanoate_dehydrogenase
• ec number:
  • EC-2.3.1.168
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 BCAA-dehydrogenase-DH-lipoyl[c] + 1 ISOBUTYRYL-COA[c] <=> 1 CO-A[c] + 1 BCAA-dehydrogenase-2MP-DH-lipoyl[c]
• With common name(s):
  • 1 an [apo BCAA dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine[c] + 1 isobutanoyl-CoA[c] <=> 1 coenzyme A[c] + 1 an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylpropanoyl]dihydrolipoyl-L-lysine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_11793
  • IN-SILICO_ANNOTATION
    • AUTOMATED-NAME-MATCH
• Tiso_gene_3260
  • EXPERIMENTAL_ANNOTATION
    • AUTOMATED-NAME-MATCH

Pathways

• PWY-5046, 2-oxoisovalerate decarboxylation to isobutanoyl-CoA: PWY-5046
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• annotation:
  • pathwaytools:
    • experimental_annotation
    • in-silico_annotation

External links

• LIGAND-RXN:
  • R02662