RXN-18210

Reaction KYNURENINASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • kynureninase
• ec number:
  • EC-3.7.1.3
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 WATER[c] + 1 CPD-14736[c] => 1 PROTON[c] + 1 ANTHRANILATE[c] + 1 L-ALPHA-ALANINE[c]
• With common name(s):
  • 1 H2O[c] + 1 L-kynurenine[c] => 1 H+[c] + 1 anthranilate[c] + 1 L-alanine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_10685
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_10684
  • IN-SILICO_ANNOTATION
    • EC-NUMBER

Pathways

• TRPCAT-PWY, L-tryptophan degradation I (via anthranilate): TRPCAT-PWY
  • 2 reactions found over 3 reactions in the full pathway
• PWY-6309, L-tryptophan degradation XI (mammalian, via kynurenine): PWY-6309
  • 9 reactions found over 17 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 16813
• LIGAND-RXN:
  • R00987
• UNIPROT:
  • Q16719
  • P70712