DHAP pi thr

Reaction PROTOHEMEFERROCHELAT-RXN

• direction:
  • REVERSIBLE
• common name:
  • ferrochelatase
• ec number:
  • EC-4.99.1.1
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROTOHEME[c] + 2 PROTON[c] <=> 1 FE+2[c] + 1 PROTOPORPHYRIN_IX[c]
• With common name(s):
  • 1 ferroheme b[c] + 2 H+[c] <=> 1 Fe2+[c] + 1 protoporphyrin IX[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_3284
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-athaliana
  • Source: orthology-synechocystis
  • Source: orthology-esiliculosus
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_15900
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-athaliana
  • Source: orthology-synechocystis
  • Source: orthology-esiliculosus
  • Source: orthology-creinhardtii

Pathways

• PWY0-1415, superpathway of heme biosynthesis from uroporphyrinogen-III: PWY0-1415
  • 5 reactions found over 6 reactions in the full pathway
• HEMESYN2-PWY, heme biosynthesis II (anaerobic): HEMESYN2-PWY
  • 3 reactions found over 4 reactions in the full pathway
• HEME-BIOSYNTHESIS-II, heme biosynthesis I (aerobic): HEME-BIOSYNTHESIS-II
  • 4 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-athaliana
    • Tool: pantograph
  • Source: orthology-creinhardtii
    • Tool: pantograph
  • Source: orthology-synechocystis
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 22584
• LIGAND-RXN:
  • R00310
• UNIPROT:
  • P22830
  • P22315
  • P28602
  • Q05338
  • P42043
  • P23871
  • P32396
  • Q9CFB4
  • P56107
  • O67083
  • Q9PI08
  • Q9JVA5
  • P22600
  • P43868
  • P16622
  • Q59735
  • P43413
  • P54225
  • P42045
  • O64391
  • P42044