1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN

Reaction 1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN

• ec number:
  • EC-2.7.1.137
• direction:
  • LEFT-TO-RIGHT
• common name:
  • phosphatidylinositol 3-kinase
  • 1-phosphatidylinositol-3-kinase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 L-1-phosphatidyl-inositols[c] + 1 ATP[c] => 1 CPD-177[c] + 1 ADP[c] + 1 PROTON[c]
• With common name(s):
  • 1 a 1-phosphatidyl-1D-myo-inositol[c] + 1 ATP[c] => 1 a 1-phosphatidyl-1D-myo-inositol 3-phosphate[c] + 1 ADP[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g4698.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g13234.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g14411.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g5530.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g4697.t1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica

Pathways

• PWY-6352, 3-phosphoinositide biosynthesis: PWY-6352
  • 6 reactions found over 8 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• UNIPROT:
  • P22543
  • Q13315
  • P32871
  • P42338
  • P42336
  • P32600
  • P35169
  • O04269
  • P91634
  • Q92213
  • P54673
  • P54674
  • P54675
  • P54677
  • O35904
  • P50520
• RHEA:
  • 12710
• LIGAND-RXN:
  • R03362