2.4.1.223-RXN

Reaction 2.4.1.223-RXN

• ec number:
  • EC-2.4.1.223
• direction:
  • LEFT-TO-RIGHT
• common name:
  • acetylglucosaminyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 UDP-N-ACETYL-D-GLUCOSAMINE[c] + 1 GlcA-Gal-Gal-Xyl-Proteins[c] => 1 GlcNAc-GlcA-Gal-Gal-Xyl-Protein[c] + 1 PROTON[c] + 1 UDP[c]
• With common name(s):
  • 1 UDP-N-acetyl-α-D-glucosamine[c] + 1 a [protein]-3-O-(β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-serine[c] => 1 a [protein]-3-O-(α-D-GlcNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-serine[c] + 1 H+[c] + 1 UDP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g13333.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g3918.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g12597.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g13999.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g3354.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g16124.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g3777.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g16773.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g16308.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g10038.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g5881.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g3675.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g14025.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g5428.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g10339.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g4675.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g18599.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g15297.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g11755.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g4004.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g4811.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g17778.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g11655.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g7975.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g6878.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g6163.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g17541.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g10283.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g11483.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g6580.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g18599.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g13335.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g10967.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g16664.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g4675.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g5907.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g16797.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g14997.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g13335.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g3777.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g3454.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g5865.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g12991.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g6976.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g9331.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g3454.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g5865.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g8354.t1
  • Source: orthology-saccharina_japonica
• Gene: g15297.t1
  • Source: orthology-saccharina_japonica
• Gene: g16902.t1
  • Source: orthology-saccharina_japonica
• Gene: g5092.t1
  • Source: orthology-saccharina_japonica
• Gene: g16773.t1
  • Source: orthology-saccharina_japonica
• Gene: g11417.t1
  • Source: orthology-saccharina_japonica
• Gene: g17932.t1
  • Source: orthology-saccharina_japonica
• Gene: g10615.t1
  • Source: orthology-saccharina_japonica
• Gene: g4675.t3
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g9331.t1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g10340.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g6250.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g4899.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g10341.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g3760.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: g8915.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g8915.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g13334.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g4449.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g10608.t1
  • Source: orthology-saccharina_japonica
• Gene: g5409.t1
  • Source: orthology-saccharina_japonica

Pathways

• PWY-6558, heparan sulfate biosynthesis (late stages): PWY-6558
  • 7 reactions found over 13 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph

External links

• RHEA:
  • 16222
• LIGAND-RXN:
  • R07397