3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN

Reaction 3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN

• ec number:
  • EC-2.1.2.11
• direction:
  • REVERSIBLE
• common name:
  • 3-methyl-2-oxobutanoate hydroxymethyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 METHYLENE-THF-GLU-N[c] + 1 2-KETO-ISOVALERATE[c] + 1 WATER[c] <=> 1 2-DEHYDROPANTOATE[c] + 1 THF-GLU-N[c]
• With common name(s):
  • 1 a 5,10-methylene-tetrahydrofolate[c] + 1 3-methyl-2-oxobutanoate[c] + 1 H2O[c] <=> 1 2-dehydropantoate[c] + 1 a tetrahydrofolate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g11566.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica

Pathways

• PANTO-PWY, phosphopantothenate biosynthesis I: PANTO-PWY
  • 4 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph

External links

• UNIPROT:
  • Q9V0E1
  • Q9JUY0
  • P31057
  • Q9PIK1
  • P38122
  • Q09672
  • P52997
  • Q9X712
  • Q9Y7B6
  • Q9L7B2
  • Q9RKS2
  • Q9RLE2
• RHEA:
  • 11827
• LIGAND-RXN:
  • R01226