DLACTDEHYDROGNAD-RXN

Reaction DLACTDEHYDROGNAD-RXN

• ec number:
  • EC-1.1.1.28
• direction:
  • LEFT-TO-RIGHT
• common name:
  • D-lactate dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PYRUVATE[c] + 1 NADH[c] + 1 PROTON[c] => 1 D-LACTATE[c] + 1 NAD[c]
• With common name(s):
  • 1 pyruvate[c] + 1 NADH[c] + 1 H+[c] => 1 (R)-lactate[c] + 1 NAD+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g12678.t1
  • Source: orthology-nannochloropsis_salina
• Gene: g4727.t1
  • Source: orthology-saccharina_japonica
• Gene: g16241.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g16496.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica

Pathways

• PWY-6454, vancomycin resistance I: PWY-6454
  • 1 reactions found over 3 reactions in the full pathway
• P122-PWY, heterolactic fermentation: P122-PWY
  • 17 reactions found over 18 reactions in the full pathway
• PWY4LZ-257, superpathway of fermentation (Chlamydomonas reinhardtii): PWY4LZ-257
  • 8 reactions found over 13 reactions in the full pathway
• PWY-6901, superpathway of glucose and xylose degradation: PWY-6901
  • 10 reactions found over 12 reactions in the full pathway
• ALACAT2-PWY, L-alanine degradation II (to D-lactate): ALACAT2-PWY
  • 3 reactions found over 3 reactions in the full pathway
• FERMENTATION-PWY, mixed acid fermentation: FERMENTATION-PWY
  • 12 reactions found over 16 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph

External links

• UNIPROT:
  • P26297
  • P26298
  • Q7M4J0
  • Q9R553
  • P06149
  • Q9JT76
  • Q9JUP8
  • P52643
  • P45295
  • P30901
  • Q89388
• RHEA:
  • 16371
• LIGAND-RXN:
  • R00704