ESTRADIOL-17-BETA-DEHYDROGENASE-RXN

Reaction ESTRADIOL-17-BETA-DEHYDROGENASE-RXN

• ec number:
  • EC-1.1.1.62
• direction:
  • LEFT-TO-RIGHT
• common name:
  • estradiol-17β dehydrogenase / estrone reductase
  • estradiol 17-beta-dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 ESTRONE[c] + 1 NADH-P-OR-NOP[c] + 1 PROTON[c] => 1 CPD-352[c] + 1 NAD-P-OR-NOP[c]
• With common name(s):
  • 1 estrone[c] + 1 NAD(P)H[c] + 1 H+[c] => 1 17β-estradiol[c] + 1 NAD(P)+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g10833.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g5421.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g4389.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM

Pathways

• PWY66-380, estradiol biosynthesis I (via estrone): PWY66-380
  • 1 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph

External links

• UNIPROT:
  • P37059
  • P70694
  • P14061
  • P37058
  • P51657
  • P51659
  • P51656
• RHEA:
  • 24618
  • 24615