FOLYLPOLYGLUTAMATESYNTH-RXN

Reaction FOLYLPOLYGLUTAMATESYNTH-RXN

• ec number:
  • EC-6.3.2.17
• direction:
  • LEFT-TO-RIGHT
• common name:
  • folylpoly-α-glutamate synthetase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 GLT[c] + 1 THF-GLU-N[c] + 1 ATP[c] => 1 THF-GLU-N[c] + 1 ADP[c] + 1 Pi[c]
• With common name(s):
  • 1 L-glutamate[c] + 1 a tetrahydrofolate[c] + 1 ATP[c] => 1 a tetrahydrofolate[c] + 1 ADP[c] + 1 phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g15296.t1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g15296.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g6417.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: g6417.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-2161, folate polyglutamylation: PWY-2161
  • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• UNIPROT:
  • P15925
  • Q9JVC6
  • P43775
  • Q9PNK6
  • Q9CGE0
  • Q50990
  • P48760
  • P08192
  • O13492
• RHEA:
  • 10581
• LIGAND-RXN:
  • R04241