GCVT-RXN

Reaction GCVT-RXN

• ec number:
  • EC-2.1.2.10
• direction:
  • REVERSIBLE
• common name:
  • aminomethyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 AMINOMETHYLDIHYDROLIPOYL-GCVH[c] + 1 THF-GLU-N[c] <=> 1 DIHYDROLIPOYL-GCVH[c] + 1 METHYLENE-THF-GLU-N[c] + 1 AMMONIUM[c]
• With common name(s):
  • 1 a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine[c] + 1 a tetrahydrofolate[c] <=> 1 a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine[c] + 1 a 5,10-methylene-tetrahydrofolate[c] + 1 ammonium[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g6869.t1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g11884.t1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g5687.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica

Pathways

• GLYCLEAV-PWY, glycine cleavage: GLYCLEAV-PWY
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• UNIPROT:
  • P25285
  • P28337
  • P27248
  • Q9UZP8
  • Q9JVP2
  • P48728
  • P49364
  • P49095
  • P49363
  • P54260
  • P49361
  • P49362
  • O49954
  • P93256
  • O32955
• RHEA:
  • 16945
• LIGAND-RXN:
  • R04125