HEME-OXYGENASE-DECYCLIZING-RXN

Reaction HEME-OXYGENASE-DECYCLIZING-RXN

• ec number:
  • EC-1.14.14.18
• direction:
  • LEFT-TO-RIGHT
• common name:
  • heme oxygenase (decyclizing)
• Synonym(s):

Reaction Formula

• With identifiers:
  • 3 OXYGEN-MOLECULE[c] + 1 PROTOHEME[c] + 3 Red-NADPH-Hemoprotein-Reductases[c] + 2 PROTON[c] => 1 BILIVERDINE[c] + 1 FE+2[c] + 1 CARBON-MONOXIDE[c] + 3 Ox-NADPH-Hemoprotein-Reductases[c] + 3 WATER[c]
• With common name(s):
  • 3 oxygen[c] + 1 ferroheme b[c] + 3 a reduced [NADPH-hemoprotein reductase][c] + 2 H+[c] => 1 biliverdin-IX-α[c] + 1 Fe2+[c] + 1 carbon monoxide[c] + 3 an oxidized [NADPH-hemoprotein reductase][c] + 3 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g4622.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica

Pathways

• PWY-5874, heme degradation I: PWY-5874
  • 1 reactions found over 2 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph

External links

• UNIPROT:
  • P23711
  • P14901
  • P30519
  • P06762
  • P09601
  • Q7M338
  • P14791
  • P32394
  • P72849
  • P74133
  • Q9RKR1
  • O48782
• RHEA:
  • 21765
• LIGAND-RXN:
  • R00311