MALATE-DEH-RXN

Reaction MALATE-DEH-RXN

• ec number:
  • EC-1.1.1.37
• direction:
  • REVERSIBLE
• common name:
  • malate dehydrogenase
• Synonym(s):
  • malate dehydrogenation

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 MAL[c] <=> 1 PROTON[c] + 1 OXALACETIC_ACID[c] + 1 NADH[c]
• With common name(s):
  • 1 NAD+[c] + 1 (S)-malate[c] <=> 1 H+[c] + 1 oxaloacetate[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g16860.t1
  • Source: orthology-nannochloropsis_salina
• Gene: g14471.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-saccharina_japonica
• Gene: g12706.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-saccharina_japonica
• Gene: g17236.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g9621.t1
  • Source: orthology-nannochloropsis_salina
• Gene: g15514.t1
  • Source: orthology-nannochloropsis_salina

Pathways

• PWY-5913, partial TCA cycle (obligate autotrophs): PWY-5913
  • 10 reactions found over 11 reactions in the full pathway
• PWY-5690, TCA cycle II (plants and fungi): PWY-5690
  • 8 reactions found over 9 reactions in the full pathway
• PWY-7115, C4 photosynthetic carbon assimilation cycle, NAD-ME type: PWY-7115
  • 9 reactions found over 9 reactions in the full pathway
• PWY-561, superpathway of glyoxylate cycle and fatty acid degradation: PWY-561
  • 6 reactions found over 8 reactions in the full pathway
• PWY66-399, gluconeogenesis III: PWY66-399
  • 11 reactions found over 12 reactions in the full pathway
• P42-PWY, incomplete reductive TCA cycle: P42-PWY
  • 5 reactions found over 7 reactions in the full pathway
• MALATE-ASPARTATE-SHUTTLE-PWY, L-aspartate degradation II: MALATE-ASPARTATE-SHUTTLE-PWY
  • 2 reactions found over 2 reactions in the full pathway
• GLUCONEO-PWY, gluconeogenesis I: GLUCONEO-PWY
  • 12 reactions found over 13 reactions in the full pathway
• GLYOXYLATE-BYPASS, glyoxylate cycle: GLYOXYLATE-BYPASS
  • 6 reactions found over 6 reactions in the full pathway
• PWY-1622, formaldehyde assimilation I (serine pathway): PWY-1622
  • 8 reactions found over 13 reactions in the full pathway
• TCA, TCA cycle I (prokaryotic): TCA
  • 9 reactions found over 10 reactions in the full pathway
• PWY-7383, anaerobic energy metabolism (invertebrates, cytosol): PWY-7383
  • 4 reactions found over 7 reactions in the full pathway
• P23-PWY, reductive TCA cycle I: P23-PWY
  • 9 reactions found over 12 reactions in the full pathway
• PWY-6969, TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): PWY-6969
  • 10 reactions found over 12 reactions in the full pathway
• PWY-6728, methylaspartate cycle: PWY-6728
  • 12 reactions found over 19 reactions in the full pathway
• PWY-5392, reductive TCA cycle II: PWY-5392
  • 6 reactions found over 12 reactions in the full pathway
• P108-PWY, pyruvate fermentation to propanoate I: P108-PWY
  • 3 reactions found over 7 reactions in the full pathway
• P105-PWY, TCA cycle IV (2-oxoglutarate decarboxylase): P105-PWY
  • 10 reactions found over 11 reactions in the full pathway
• PWY66-398, TCA cycle III (animals): PWY66-398
  • 10 reactions found over 11 reactions in the full pathway
• FERMENTATION-PWY, mixed acid fermentation: FERMENTATION-PWY
  • 12 reactions found over 16 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph

External links

• UNIPROT:
  • Q07841
  • P33163
  • P44427
  • Q9PHY2
  • P22133
  • P17505
  • P32419
  • P25077
  • P14152
  • Q8R1P0
  • P19446
  • P17783
  • P04636
  • P58408
  • Q58820
  • P49814
  • Q93ZA7
  • Q7M4Y9
  • Q7M4Z0
  • P10887
  • P11386
  • P19983
  • P19981
  • P19979
  • P19977
  • P19982
  • P19978
  • P19980
  • P16142
  • P46487
  • P46488
  • Q43744
  • Q59202
  • Q55383
  • Q42972
  • O81278
  • O81279
  • O65363
  • O65364
  • O81609
  • Q43743
  • Q42686
  • P93106
  • Q04820
  • O48903
  • O48904
  • O48905
  • O48906
  • O24047
  • Q9XTB4
  • P50917
  • Q49981
  • Q9ZP05
  • Q9ZP06
  • Q9SN86
• PIR:
  • A32472
  • A49496
  • A60689
  • C64110
  • D81399
  • DEBYMC
  • DEBYMM
  • DEBYMP
  • DEEBM
  • DEECM
  • DEMSMC
  • DEMSMM
  • DEPGMM
  • DEPUGW
  • DEPUMW
  • DERTMM
  • DETWMA
  • F85551
  • G01650
  • H64477
  • I40383
  • PA0040
  • PA0079
  • PN0162
  • S03352
  • S03958
  • S04956
  • S04957
  • S04958
  • S04959
  • S04960
  • S04961
  • S07574
  • S08981
  • S44167
  • S52039
  • S57958
  • S61213
  • S75735
  • T03272
  • T06325
  • T06326
  • T06327
  • T06328
  • T06386
  • T08015
  • T08077
  • T08177
  • T09228
  • T09263
  • T09286
  • T09291
  • T09294
  • T12433
  • T18570
  • T45206
  • T45208
  • T49932
  • T51311
  • T51862
• RHEA:
  • 21435
• LIGAND-RXN:
  • R00342