QUINOPRIBOTRANS-RXN

Reaction QUINOPRIBOTRANS-RXN

• ec number:
  • EC-2.4.2.19
• direction:
  • LEFT-TO-RIGHT
• common name:
  • nicotinate-nucleotide diphosphorylase (carboxylating)
  • quinolinate phosphoribosyltransferase (decarboxylating)
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 QUINOLINATE[c] + 2 PROTON[c] + 1 PRPP[c] => 1 NICOTINATE_NUCLEOTIDE[c] + 1 PPI[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 quinolinate[c] + 2 H+[c] + 1 5-phospho-α-D-ribose 1-diphosphate[c] => 1 β-nicotinate D-ribonucleotide[c] + 1 diphosphate[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g9429.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g6645.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g3741.t1
  • Source: orthology-saccharina_japonica
• Gene: g17229.t1
  • Source: orthology-saccharina_japonica
• Gene: g17694.t1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g8192.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-saccharina_japonica

Pathways

• PWY-5316, nicotine biosynthesis: PWY-5316
  • 3 reactions found over 9 reactions in the full pathway
• PWY-7342, superpathway of nicotine biosynthesis: PWY-7342
  • 4 reactions found over 13 reactions in the full pathway
• PYRIDNUCSYN-PWY, NAD biosynthesis I (from aspartate): PYRIDNUCSYN-PWY
  • 6 reactions found over 6 reactions in the full pathway
• PWY-5653, NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde: PWY-5653
  • 3 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• UNIPROT:
  • Q9JSX8
  • Q57916
  • P30011
  • P46714
  • Q15274
  • P77938
• RHEA:
  • 12735
• LIGAND-RXN:
  • R03348