RXN-11321

Reaction RXN-11321

• ec number:
  • EC-1.14.11.30
• direction:
  • LEFT-TO-RIGHT
• common name:
  • hypoxia-inducible factor-asparagine dioxygenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 HIF-Alpha[c] + 1 2-KETOGLUTARATE[c] + 1 OXYGEN-MOLECULE[c] => 1 CARBON-DIOXIDE[c] + 1 3-hydroxy-L-asparagine-HIF-Alpha[c] + 1 SUC[c]
• With common name(s):
  • 1 a hypoxia inducible factor (HIF) α subunit[c] + 1 2-oxoglutarate[c] + 1 oxygen[c] => 1 CO2[c] + 1 a (3S)-3-hydroxy-L-asparagine-HIF α subunit[c] + 1 succinate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g12297.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g4167.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g6639.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g12139.t2
  • Source: orthology-saccharina_japonica
• Gene: g13655.t1
  • Source: orthology-saccharina_japonica
• Gene: g12297.t1
  • Source: orthology-saccharina_japonica
• Gene: g12139.t1
  • Source: orthology-saccharina_japonica

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph