RXN-11662

Reaction RXN-11662

• ec number:
  • EC-1.1.1.35
• direction:
  • REVERSIBLE
• common name:
  • (S)-3-hydroxybutanoyl-CoA dehydrogeanse
  • 3-hydroxyacyl-CoA dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 S-3-HYDROXYBUTANOYL-COA[c] + 1 NAD[c] <=> 1 NADH[c] + 1 PROTON[c] + 1 ACETOACETYL-COA[c]
• With common name(s):
  • 1 (S)-3-hydroxybutanoyl-CoA[c] + 1 NAD+[c] <=> 1 NADH[c] + 1 H+[c] + 1 acetoacetyl-CoA[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g3371.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g7899.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g10833.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g17267.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g12553.t1
  • Source: orthology-saccharina_japonica
• Gene: g10495.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-saccharina_japonica
• Gene: g3370.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-arabidopsis_thaliana
• Gene: g14423.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-saccharina_japonica
• Gene: g10495.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-saccharina_japonica
• Gene: g3527.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica

Pathways

• CENTFERM-PWY, pyruvate fermentation to butanoate: CENTFERM-PWY
  • 5 reactions found over 7 reactions in the full pathway
• PWY-7779, methyl tert-butyl ether degradation: PWY-7779
  • 2 reactions found over 10 reactions in the full pathway
• PWY-7778, 2-methylpropene degradation: PWY-7778
  • 3 reactions found over 8 reactions in the full pathway
• PWY-6863, pyruvate fermentation to hexanol (engineered): PWY-6863
  • 8 reactions found over 11 reactions in the full pathway
• PWY-7401, crotonate fermentation (to acetate and cyclohexane carboxylate): PWY-7401
  • 6 reactions found over 17 reactions in the full pathway
• PWY-5177, glutaryl-CoA degradation: PWY-5177
  • 5 reactions found over 5 reactions in the full pathway
• PWY-6583, pyruvate fermentation to butanol I: PWY-6583
  • 6 reactions found over 8 reactions in the full pathway
• PWY-5789, 3-hydroxypropanoate/4-hydroxybutanate cycle: PWY-5789
  • 10 reactions found over 18 reactions in the full pathway
• PWY-6883, pyruvate fermentation to butanol II (engineered): PWY-6883
  • 5 reactions found over 6 reactions in the full pathway
• PWY-7216, (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered): PWY-7216
  • 3 reactions found over 5 reactions in the full pathway
• P162-PWY, L-glutamate degradation V (via hydroxyglutarate): P162-PWY
  • 7 reactions found over 11 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph

External links

• RHEA:
  • 30802
• LIGAND-RXN:
  • R01975