RXN-11887

Reaction RXN-11887

• ec number:
  • EC-1.14.19.20
• direction:
  • LEFT-TO-RIGHT
• common name:
  • 5α-cholest-7,24-dien-3β-ol,NAD(P)H:oxygen 5-oxidoreductase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 5-ALPHA-CHOLESTA-724-DIEN-3-BETA-OL[c] + 2 FERROCYTOCHROME-B5[c] + 1 OXYGEN-MOLECULE[c] + 2 PROTON[c] => 1 CPD-8646[c] + 2 FERRICYTOCHROME-B5[c] + 2 WATER[c]
• With common name(s):
  • 1 5α-cholesta-7,24-dien-3β-ol[c] + 2 a ferrocytochrome b5[c] + 1 oxygen[c] + 2 H+[c] => 1 7-dehydrodesmosterol[c] + 2 a ferricytochrome b5[c] + 2 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g18148.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g5475.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica

Pathways

• PWY66-4, cholesterol biosynthesis III (via desmosterol): PWY66-4
  • 12 reactions found over 22 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph

External links

• RHEA:
  • 34004