RXN-12124

Reaction RXN-12124

• ec number:
  • EC-1.3.99.5
• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-oxo-5-alpha-steroid 4-dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-342[c] + 1 Acceptor[c] => 1 ANDROST4ENE[c] + 1 Donor-H2[c]
• With common name(s):
  • 1 5α-androstane-3,17-dione[c] + 1 an oxidized electron acceptor[c] => 1 androst-4-ene-3,17-dione[c] + 1 a reduced electron acceptor[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g4721.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g9245.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g9244.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g12550.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM

Pathways

• PWY-6943, testosterone and androsterone degradation to androstendione: PWY-6943
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph

External links

• RHEA:
  • 51049