RXN-12353

Reaction RXN-12353

• ec number:
  • EC-1.14.11.33
• direction:
  • LEFT-TO-RIGHT
• common name:
  • DNA oxidative demethylase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 OXYGEN-MOLECULE[c] + 1 Methylated-DNA-Bases[c] + 1 2-KETOGLUTARATE[c] => 1 Nucleobases-in-DNA[c] + 1 CARBON-DIOXIDE[c] + 1 FORMALDEHYDE[c] + 1 SUC[c]
• With common name(s):
  • 1 oxygen[c] + 1 a methylated nucleobase within DNA[c] + 1 2-oxoglutarate[c] => 1 a nucleobase within DNA[c] + 1 CO2[c] + 1 formaldehyde[c] + 1 succinate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g11116.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g8109.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph

External links

• RHEA:
  • 30300