RXN-12583

Reaction RXN-12583

• direction:
  • LEFT-TO-RIGHT
• common name:
  • pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)
  • pyruvate dehydrogenase (NAD+)
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROTON[c] + 1 PYRUVATE[c] + 1 THIAMINE-PYROPHOSPHATE[c] => 1 2-ALPHA-HYDROXYETHYL-THPP[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 H+[c] + 1 pyruvate[c] + 1 thiamine diphosphate[c] => 1 2-(α-hydroxyethyl)thiamine diphosphate[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g6722.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-saccharina_japonica
• Gene: g6561.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g16637.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-saccharina_japonica
• Gene: g11188.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-saccharina_japonica
• Gene: g14052.t1
  • Source: orthology-saccharina_japonica

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R00014