RXN-13186

Reaction RXN-13186

• ec number:
  • EC-1.14.11.27
• direction:
  • LEFT-TO-RIGHT
• common name:
  • histone demethylase activity (H3-K36 specific)
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 2-KETOGLUTARATE[c] + 2 OXYGEN-MOLECULE[c] + 1 PROTON[c] + 1 CPD-8900[c] => 1 Protein-L-lysine[c] + 2 SUC[c] + 2 FORMALDEHYDE[c] + 2 CARBON-DIOXIDE[c]
• With common name(s):
  • 2 2-oxoglutarate[c] + 2 oxygen[c] + 1 H+[c] + 1 a [protein] N6,N6-dimethyl-L-lysine[c] => 1 a [protein]-L-lysine[c] + 2 succinate[c] + 2 formaldehyde[c] + 2 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g18712.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g8810.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g12822.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g8614.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g7683.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g16687.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g8811.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph

External links

• RHEA:
  • 42033
• LIGAND-RXN:
  • R10056