RXN-14326

Reaction RXN-14326

• ec number:
  • EC-2.1.1.98
• direction:
  • LEFT-TO-RIGHT
• common name:
  • diphthine synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 3 S-ADENOSYLMETHIONINE[c] + 1 2-3-CARBOXY-3-AMINOPROPYL-L-HISTIDINE[c] => 1 DIPHTINE[c] + 3 ADENOSYL-HOMO-CYS[c] + 3 PROTON[c]
• With common name(s):
  • 3 S-adenosyl-L-methionine[c] + 1 a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2][c] => 1 a diphthine-[translation elongation factor 2][c] + 3 S-adenosyl-L-homocysteine[c] + 3 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g8266.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g15487.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g15487.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM

Pathways

• PWY-6482, diphthamide biosynthesis (archaea): PWY-6482
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph

External links

• RHEA:
  • 36416
• LIGAND-RXN:
  • R10306