RXN-15775

Reaction RXN-15775

• ec number:
  • EC-2.1.1.314
• direction:
  • LEFT-TO-RIGHT
• common name:
  • diphthine synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 4 S-ADENOSYLMETHIONINE[c] + 1 2-3-CARBOXY-3-AMINOPROPYL-L-HISTIDINE[c] => 1 Diphthine-methyl-ester-EF2[c] + 4 ADENOSYL-HOMO-CYS[c] + 3 PROTON[c]
• With common name(s):
  • 4 S-adenosyl-L-methionine[c] + 1 a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2][c] => 1 a diphthine methyl ester-[translation elongation factor 2][c] + 4 S-adenosyl-L-homocysteine[c] + 3 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g15487.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g8266.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g15487.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER

Pathways

• PWY-7546, diphthamide biosynthesis (eukaryotes): PWY-7546
  • 4 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• RHEA:
  • 42653