RXN-5466

Reaction RXN-5466

• ec number:
  • EC-2.4.1.258
• direction:
  • LEFT-TO-RIGHT
• common name:
  • dolichyl-P-Man:Man5GlcNAc2-PP-dolichol α-1,3-mannosyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-171[c] + 1 CPD-5164[c] => 1 CPD-5165[c] + 1 DOLICHOLP[c] + 1 PROTON[c]
• With common name(s):
  • 1 a dolichyl β-D-mannosyl phosphate[c] + 1 α-D-Man-(1→2)-α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol[c] => 1 α-D-Man-(1→2)-α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→3)-α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol[c] + 1 a dolichyl phosphate[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g11715.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica

Pathways

• MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS, protein N-glycosylation initial phase (eukaryotic): MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
  • 14 reactions found over 19 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• RHEA:
  • 29530
• LIGAND-RXN:
  • R06258