RXN-8642

Reaction RXN-8642

• direction:
  • REVERSIBLE
• common name:
  • NADP-dependent isocitrate dehydrogenase
• Synonym(s):
  • oxalsuccinic decarboxylase
  • isocitrate (NADP) dehydrogenase
  • isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase
  • NADP-specific isocitrate dehydrogenase
  • NADP-linked isocitrate dehydrogenase
  • NADP isocitric dehydrogenase
  • isocitrate dehydrogenase (NADP-dependent)
  • NADP-dependent isocitric dehydrogenase
  • triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase
  • NADP+-linked isocitrate dehydrogenase
  • IDH (ambiguous)
  • dual-cofactor-specific isocitrate dehydrogenase
  • NADP+-ICDH
  • NADP+-IDH
  • IDP
  • IDP1
  • IDP2
  • IDP3

Reaction Formula

• With identifiers:
  • 1 OXALO-SUCCINATE[c] + 1 PROTON[c] <=> 1 2-KETOGLUTARATE[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 oxalosuccinate[c] + 1 H+[c] <=> 1 2-oxoglutarate[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g10656.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• RHEA:
  • 19384
• LIGAND-RXN:
  • R00268