RXN-8647

Reaction RXN-8647

• direction:
  • LEFT-TO-RIGHT
• common name:
  • (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyicosa-6,8,11,14-tetraenoate dehydratase
  • arachidonate 5-lipoxygenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 6E8Z11Z14Z-5S-5-HYDROPEROXYCOSA-6[c] => 1 CPD-8892[c] + 1 WATER[c]
• With common name(s):
  • 1 (5S)-HPETE[c] => 1 leukotriene A4[c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g6085.t1
  • Source: orthology-saccharina_japonica
• Gene: g11424.t1
  • Source: orthology-saccharina_japonica
• Gene: g12029.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g12029.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER

Pathways

• PWY66-375, leukotriene biosynthesis: PWY66-375
  • 5 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• RHEA:
  • 17962
• LIGAND-RXN:
  • R03058