RXN-8853

Reaction RXN-8853

• ec number:
  • EC-1.1.1.153
• direction:
  • LEFT-TO-RIGHT
• common name:
  • sepiapterin reductase [(6R)-tetrahydrobiopterin-forming]
  • 5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 PROTON[c] + 1 6-PYRUVOYL-5678-TETRAHYDROPTERIN[c] + 2 NADPH[c] => 1 CPD-14053[c] + 2 NADP[c]
• With common name(s):
  • 2 H+[c] + 1 (6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin[c] + 2 NADPH[c] => 1 (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin[c] + 2 NADP+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g7084.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica

Pathways

• PWY-5663, erythro-tetrahydrobiopterin biosynthesis I: PWY-5663
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph

External links

• RHEA:
  • 24740
• LIGAND-RXN:
  • R08208

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