RXN-9847

Reaction RXN-9847

• ec number:
  • EC-4.2.1.107
• direction:
  • LEFT-TO-RIGHT
• common name:
  • (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA hydratase
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-10589[c] + 1 WATER[c] => 1 CPD-10590[c]
• With common name(s):
  • 1 (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA[c] + 1 H2O[c] => 1 (24R,25R)-3α,7α,24-trihydroxy-5β-cholestanoyl CoA[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g10495.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g10495.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica

Pathways

• PWY-6061, bile acid biosynthesis, neutral pathway: PWY-6061
  • 3 reactions found over 29 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph

External links

• RHEA:
  • 18934
• LIGAND-RXN:
  • R04809