RXN0-1134

Reaction RXN0-1134

• ec number:
  • EC-1.2.4.1
• direction:
  • LEFT-TO-RIGHT
• common name:
  • pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase
  • pyruvate dehydrogenase (NAD+)
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PYRUVATE[c] + 1 Pyruvate-dehydrogenase-lipoate[c] + 1 PROTON[c] => 1 Pyruvate-dehydrogenase-acetylDHlipoyl[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 pyruvate[c] + 1 a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] + 1 H+[c] => 1 a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g6561.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g16637.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g11188.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g6722.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g14052.t1
  • Source: orthology-saccharina_japonica

Pathways

• PYRUVDEHYD-PWY, pyruvate decarboxylation to acetyl CoA: PYRUVDEHYD-PWY
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph

External links

• UNIPROT:
  • P06959
  • P26267
  • P35485
  • Q59097
  • Q9N1X8
  • P45119
  • P11966
  • P35488
  • P47515
  • P21882
  • P47516
  • P21881
  • P21873
  • P16387
  • P0AFG8
  • P08559
  • P11177
  • P29803
  • P29804
  • P26284
  • Q9JU08
  • Q9CJD6
  • Q9JU07
  • Q9CJD5
  • Q09171
  • P52901
  • P79931
  • P79932
  • Q9D051
  • P10801
  • P21874
  • P49432
  • Q59820
  • P35486
  • P35487
  • Q06437
  • P32473
  • Q59107
  • P73405
  • Q49109
  • O48685
  • P52902
  • P52904
  • P52903
  • O66112
  • Q9Y8I5
  • Q9Y8I6
  • O69478
  • P10802
• LIGAND-RXN:
  • R01699

"pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase" cannot be used as a page name in this wiki.