RXN66-343

Reaction RXN66-343

• ec number:
  • EC-1.3.1.22
• direction:
  • LEFT-TO-RIGHT
• common name:
  • testosterone reductase
  • testosterone 5α-reductase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 TESTOSTERONE[c] + 1 PROTON[c] + 1 NADPH[c] => 1 NADP[c] + 1 17-BETA-HYDROXY-5ALPHA-ANDROSTAN-3-O[c]
• With common name(s):
  • 1 testosterone[c] + 1 H+[c] + 1 NADPH[c] => 1 NADP+[c] + 1 17-β-hydroxy-5-α-androstan-3-one[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g4721.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g9245.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g12550.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g9244.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER

Pathways

• PWY66-378, androgen biosynthesis: PWY66-378
  • 4 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools