DHFR

Reaction DHFR

• direction:
  • REVERSIBLE
• common name:
  • Dihydrofolate reductase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 nadph[c] + 1.0 h[c] + 1.0 dhf[c] <=> 1.0 thf[c] + 1.0 nadp[c]
• With common name(s):
  • 1.0 Nicotinamide adenine dinucleotide phosphate - reduced[c] + 1.0 H+[c] + 1.0 7,8-Dihydrofolate[c] <=> 1.0 5,6,7,8-Tetrahydrofolate[c] + 1.0 Nicotinamide adenine dinucleotide phosphate[c]

Pathways

• map01100: map01100
  • 471 reactions found over 2349 reactions in the full pathway
• map00670: map00670
  • 13 reactions found over 65 reactions in the full pathway
• map00790: map00790
  • 10 reactions found over 41 reactions in the full pathway

Reconstruction information

• Category: manual
  • Source: manual-reaction_to_add_delete
    • Comment: reaction added from literature evidence or biological expertise

External links

• RHEA:
  • 15009
• Reactome : REACT_R-BTA-197972
• MetaNetX (MNX) Equation : MNXR97401
• KEGG Reaction : R00939
• EC Number : 1.5.1.3